MARY LEE ESTY, PHD
Social Work at Woodmont Ave, Bethesda, MD

License number
Maryland 05913
Category
Social Work
Type
Clinical
Address
Address
7910 Woodmont Ave SUITE 305, Bethesda, MD 20814
Phone
(301) 215-7721
(301) 215-7718 (Fax)

Professional information

Mary Esty Photo 1

Method And Apparatus For Utilizing Amplitude-Modulated Pulse-Width Modulation Signals For Neurostimulation And Treatment Of Neurological Disorders Using Electrical Stimulation

US Patent:
8280502, Oct 2, 2012
Filed:
Apr 22, 2010
Appl. No.:
12/765561
Inventors:
Jeffrey B. Hargrove - Bancroft MI, US
Theodore J. Stokes - Lapeer MI, US
Mary L. Esty - Chevy Chase MD, US
Assignee:
Cerephex Corporation - Bancroft MI
International Classification:
A61B 5/04
US Classification:
600544
Abstract:
A computing device-controlled system is described for the generation of amplitude-modulated pulse-width modulation (AMPWM) signals for use in treating neurological dysfunction via cranial neurostimulation, where the AMPWM signal is specifically designed to minimize the electrical impedance of the tissues of the head. A low-frequency carrier signal is determined for the AMPWM signal by measuring EEG activity at a reference site or sites, generally corresponding with the location of suspected brain dysfunction. Carrier signal frequency is variably related to critical frequency components of the EEG power spectral density, determined from statistical analysis of amplitudes and variability, and dynamically changed as a function of time to prevent entrainment. The AMPWM signal is presented to a subject via a plurality of neurostimulation delivery modes for therapeutic use.


Mary Esty Photo 2

Method And Apparatus For Utilizing Amplitude-Modulated Pulse-Width Modulation Signals For Neurostimulation And Treatment Of Neurological Disorders Using Electrical Stimulation

US Patent:
2006025, Nov 16, 2006
Filed:
Jul 21, 2006
Appl. No.:
11/490255
Inventors:
Jeffrey Hargrove - Bancroft MI, US
Theodore Stokes - Lapeer MI, US
Mary Esty - Chevy Chase MD, US
International Classification:
A61B 5/04
US Classification:
600544000
Abstract:
A computing device-controlled system is described for the generation of amplitude-modulated pulse-width modulation (AMPWM) signals for use in treating neurological dysfunction via cranial neurostimulation, where the AMPWM signal is specifically designed to minimize the electrical impedance of the tissues of the head. A low-frequency carrier signal is determined for the AMPWM signal by measuring EEG activity at a reference site or sites, generally corresponding with the location of suspected brain dysfunction. Carrier signal frequency is variably related to critical frequency components of the EEG power spectral density, determined from statistical analysis of amplitudes and variability, and dynamically changed as a function of time to prevent entrainment. The AMPWM signal is presented to a subject via a plurality of neurostimulation delivery modes for therapeutic use.