DR. MARY K CROW, M.D.
Osteopathic Medicine at 70 St, New York, NY
License number
New York 138538
Category
Osteopathic Medicine
Type
Rheumatology
Address
Address
535 E 70Th St, New York, NY 10021
Phone
(212) 606-1397
(212) 774-2337 (Fax)
(212) 774-2337 (Fax)
Personal information
See more information about MARY K CROW at radaris.comName
Address
Phone
47 Spring St, Springville, NY 14141
17 E 89Th St, New York, NY 10128
17 89Th St, New York, NY 10128
Professional information
Senior Scientist At Hospital For Special Surgery
Position:
Senior Scientist at Hospital for Special Surgery
Location:
Greater New York City Area
Industry:
Hospital & Health Care
Work:
Hospital for Special Surgery
-
Senior Scientist
Manager At Staples
Position:
manager at Staples
Location:
Greater New York City Area
Industry:
Retail
Work:
Staples
-
manager
Mary Kuntz Crow, New York NY
Specialties:
Rheumatologist
Address:
535 E 70Th St, New York, NY 10021
525 E 68Th St, New York, NY 10065
525 E 68Th St, New York, NY 10065
Education:
Cornell University, Weill Cornell Medical College - Doctor of Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Rheumatology (Internal Medicine)
Mary Kuntz Crow, New York NY
Specialties:
Internal Medicine, Rheumatology
Work:
Hospital For Special Surgery
535 E 70Th St, New York, NY 10021
535 E 70Th St, New York, NY 10021
Education:
Cornell University (1978)
Method Of Producing Antibodies To A Restricted Population Of T Lymphocytes, Antibodies Produced Therefrom And Methods Of Use Thereof
US Patent:
5480895, Jan 2, 1996
Filed:
Sep 27, 1991
Appl. No.:
7/766751
Inventors:
Steven M. Friedman - Tenafly NJ
Mary K. Crow - New York NY
David Posnett - New York NY
Mary K. Crow - New York NY
David Posnett - New York NY
Assignee:
New York Society for the Relief of the Ruptured and Crippled,
Maintaining the Hospital for Special Surgery - New York NY
Maintaining the Hospital for Special Surgery - New York NY
International Classification:
G01N 33577
US Classification:
435 724
Abstract:
This invention relates to a method of obtaining antibodies specific to a population of T-lymphocytes (T cells) restricted by V. beta. gene usage. The invention also relates to the antibodies obtained and to methods of using them. According to the invention, T cells are incubated with an effective amount of a superantigen under conditions and for a time sufficient to allow division and growth of T-cells reactive to the superantigen. The incubated T-cells are injected into a mammal, and thereafter serum containing antibodies specific to the incubated and injected T-cells is removed from the mammal.
Method Of Producing Antibodies To A Restricted Population Of T Lymphocytes Antibodies Produced Therefrom And Methods Of Use Thereof
US Patent:
5786159, Jul 28, 1998
Filed:
Jan 25, 1995
Appl. No.:
8/377930
Inventors:
Steven M. Friedman - Tenafly NJ
Mary K. Crow - New York NY
David Posnett - New York NY
Mary K. Crow - New York NY
David Posnett - New York NY
Assignee:
New York Society for the Ruptured and Crippled Maintaining the Hospital
for Special Surgery - New York NY
for Special Surgery - New York NY
International Classification:
G01N 33577
US Classification:
435724
Abstract:
Antibodies to specific subsets of T cells can be obtained by incubating a polyclonal population of T cells with a microbial superantigen, and injecting of the incubated T cells into a host animal. Antibodies obtained by this method and methods of use thereof are also provided.
Dna Encoding Conserved T-Cell Receptor Sequences
US Patent:
6084087, Jul 4, 2000
Filed:
Oct 28, 1997
Appl. No.:
8/963121
Inventors:
Steven M. Friedman - Tenafly NJ
Mary K. Crow - New York NY
Yixin Li - New York NY
Joseph R. Tumang - Woodhaven NY
Guang-Rong Sun - New York NY
Mary K. Crow - New York NY
Yixin Li - New York NY
Joseph R. Tumang - Woodhaven NY
Guang-Rong Sun - New York NY
Assignee:
New York Society For the Ruptured and Crippled Maintaing the Hospital
for Special Surgery - New York NY
for Special Surgery - New York NY
International Classification:
C12N 1512, C07K 14725
US Classification:
536 235
Abstract:
Four unique transcripts have been isolated from the. beta. chain of the T cell receptor in T cells in the synovial tissue of a patient with rheumatoid arthritis. Two of these transcripts were isolated from fresh synovial tissue and two were isolated from a T cell line derived from the synovial tissue. The sequences of the four transcripts are highly homologous, with a conserved amino acid sequence of IGQ. sub. -- N in the highly diverse V-D junction. The. alpha. chain and the antigenic specificity of the T cell line derived transcripts has also been characterized.
Conserved T-Cell Receptor Sequences
US Patent:
6303750, Oct 16, 2001
Filed:
Apr 6, 2000
Appl. No.:
9/543513
Inventors:
Steven M. Friedman - Tenafly NJ
Mary K. Crow - New York NY
Yixin Li - New York NY
Joseph R. Tumang - Woodhaven NY
Guang-Rong Sun - New York NY
Mary K. Crow - New York NY
Yixin Li - New York NY
Joseph R. Tumang - Woodhaven NY
Guang-Rong Sun - New York NY
Assignee:
New York Society for the Ruptured and Crippled Maintaining the Hopital for
Special Surgery - New York NY
Special Surgery - New York NY
International Classification:
C07K 14725, C12N 1512
US Classification:
530324
Abstract:
Four unique transcripts have been isolated from the. beta. chain of the T cell receptor in T cells in the synovial tissue of a patient with rheumatoid arthritis. Two of these transcripts were isolated from fresh synovial tissue and two were isolated from a T cell line derived from the synovial tissue. The sequences of the four transcripts are highly homologous, with a conserved amino acid sequence of IGQ_N in the highly diverse V-D junction. The. alpha. chain and the antigenic specificity of the T cell line derived transcripts has also been characterized.
Methods Of Determining Disease Activity In Sle Patients By Correlating The Level Of Soluble Cd40 Ligand
US Patent:
6117642, Sep 12, 2000
Filed:
Nov 7, 1997
Appl. No.:
8/966123
Inventors:
Mary K. Crow - New York NY
Radha Krishna Vakkalanka - New York NY
Radha Krishna Vakkalanka - New York NY
Assignee:
New York Society for the Relief of the Ruptured and Crippled Maintaining
the Hospital for Special Surgery - New York NY
the Hospital for Special Surgery - New York NY
International Classification:
G01N 3353, G01N 33536
US Classification:
435 71
Abstract:
The present invention provides diagnostic methods for determining the severity of disease or disease activity in patients suffering from autoimmune, inflammatory, malignant, vascular, or viral diseases, which involves measuring the level of CD40 ligand (CD40L) in the patient's serum or other body fluid.
Markers For Disease Susceptibility And Targets For Therapy
US Patent:
2003000, Jan 2, 2003
Filed:
Dec 19, 2001
Appl. No.:
10/025201
Inventors:
Mary Crow - New York NY, US
Assignee:
Hospital for Special Surgery
International Classification:
C12Q001/68
US Classification:
435/006000
Abstract:
The invention provides novel methods for determining susceptibility for, diagnosing, and/or treating complex diseases such as autoimmune diseases, Alzheimer's disease, and schizophrenia. The novel methods are based upon the finding that the positioning of long interspersed nuclear elements (LINEs) in the genome can play an important role in the induction and progression of complex diseases. Specifically, the distance and interaction between a LINE such as the L1 element and a susceptibility gene associated with a complex diseases can provide information about the risk for the complex disease, and also provide novel targets for therapy.