MARY GILES CARTER
Architects in Arlington, MA
License number
Massachusetts 6217
Issued Date
Oct 9, 1985
Expiration Date
Aug 31, 2002
Type
Architect
Address
Address
Arlington, MA 02476
Professional information
Pyrazolopyridines And Methods Of Making And Using The Same
US Patent:
7691865, Apr 6, 2010
Filed:
Sep 5, 2003
Appl. No.:
10/526839
Inventors:
Mary Beth Carter - Arlington MA, US
Lihong Sun - Arlington MA, US
Paul Lyne - Arlington MA, US
Claudio Chuaqui - Somerville MA, US
Zhongli Zheng - Lexington MA, US
Juswinder Singh - Ashland MA, US
Lihong Sun - Arlington MA, US
Paul Lyne - Arlington MA, US
Claudio Chuaqui - Somerville MA, US
Zhongli Zheng - Lexington MA, US
Juswinder Singh - Ashland MA, US
Assignee:
Biogen Idec MA Inc. - Cambridge MA
International Classification:
A61K 31/519, C07D 471/02, C07D 487/04
US Classification:
5142593, 514303, 544281, 546117
Abstract:
Compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I:.
Novel Cd40:Cd154 Binding Interruptor Compounds And Use Thereof To Treat Immunological Complications
US Patent:
2007024, Oct 25, 2007
Filed:
Feb 2, 2007
Appl. No.:
11/701983
Inventors:
Zhongli Zheng - Lexington MA, US
Mary Carter - Arlington MA, US
YuSheng Liao - Lexington MA, US
Lihong Sun - Arlington MA, US
Leonid Kirkovsky - San Diego CA, US
Susan Mrose - Brookline MA, US
Yen-Ming Hsu - Lexington MA, US
David Thomas - Houston TX, US
Gerald Shipps - Stoneham MA, US
Satish Jindal - Milton MA, US
George Lenz - Andover MA, US
Huw Nash - Cambridge MA, US
Mary Carter - Arlington MA, US
YuSheng Liao - Lexington MA, US
Lihong Sun - Arlington MA, US
Leonid Kirkovsky - San Diego CA, US
Susan Mrose - Brookline MA, US
Yen-Ming Hsu - Lexington MA, US
David Thomas - Houston TX, US
Gerald Shipps - Stoneham MA, US
Satish Jindal - Milton MA, US
George Lenz - Andover MA, US
Huw Nash - Cambridge MA, US
International Classification:
A61K 31/44, A61P 37/08, C07C 303/00, C07D 213/44
US Classification:
514332000, 546262000, 564080000
Abstract:
The present invention relates to novel CD40:CD154 binding interrupter compounds and use of these compounds and pharmaceutical compositions comprising them, to treat conditions associated with inappropriate CD154 activation in a subject. Specifically, this invention provides compounds which are identified by screening a library of small molecules for those that are capable of specifically binding CD154 and interrupting CD40:CD154 interaction.
Pyrazoles And Methods Of Making And Using The Same
US Patent:
2006026, Nov 23, 2006
Filed:
Feb 12, 2004
Appl. No.:
10/545179
Inventors:
Lihong Sun - Arlington MA, US
Feng Shan - Braintree MA, US
Claudio Chuaqui - Somerville MA, US
Mark Cornebise - Watertown MA, US
Timothy Pontz - Brighton MA, US
Mary Carter - Arlington MA, US
Juswinder Singh - Ashland MA, US
Leona Ling - Winchester MA, US
Russell Petter - Stow MA, US
Feng Shan - Braintree MA, US
Claudio Chuaqui - Somerville MA, US
Mark Cornebise - Watertown MA, US
Timothy Pontz - Brighton MA, US
Mary Carter - Arlington MA, US
Juswinder Singh - Ashland MA, US
Leona Ling - Winchester MA, US
Russell Petter - Stow MA, US
Assignee:
BIOGEN IDEC MA INC. - Cambridge MA
International Classification:
A61K 31/522, A61K 31/52, A61K 31/519, A61K 31/517, C07D 473/02, C07D 487/04
US Classification:
514249000, 544238000, 544235000, 544281000, 544284000, 544353000, 544277000, 544278000, 514252020, 514252040, 514263200, 514260100, 514259100, 514266200, 514266210
Abstract:
The invention is based on the discovery that compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I (I).
Imidazolopyridines And Methods Of Making And Using The Same
US Patent:
2006013, Jun 22, 2006
Filed:
Sep 5, 2003
Appl. No.:
10/526653
Inventors:
Mary Carter - Arlington MA, US
Lihong Sun - Arlington MA, US
Claudio Chuaqui - Somerville MA, US
Juswinder Singh - Ashland MA, US
Michael Choi - Cambridge MA, US
Lihong Sun - Arlington MA, US
Claudio Chuaqui - Somerville MA, US
Juswinder Singh - Ashland MA, US
Michael Choi - Cambridge MA, US
International Classification:
A61K 31/5377, C07D 471/02, A61K 31/506
US Classification:
514234500, 514303000, 514275000, 544127000, 544331000
Abstract:
Compounds of formula I possess unexpectedly high affinity for Alk 5 and/or Alk 4, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including fibrotic disorders. In one embodiment, the invention features a compound of formula I: