Inventors:
Mary Elizabeth Patti - Newton MA, US
Wanzhu Jin - Brookline MA, US
Allison B. Goldfine - Wayland MA, US
Assignee:
Joslin Diabetes Center, Inc. - Boston MA
International Classification:
A61K 48/00, A61K 31/166, A61K 31/4025, A61P 3/00
Abstract:
Described are methods of improving glycemic control/improving insulin sensitivity by administering an inhibitor of serum response factor (SRF) activity, and methods of identifying new compounds for use in the described methods of treatment.