Inventors:
Devkumar Mustafi - Chicago IL, US
Gregory S. Karczmar - Crete IL, US
Marvin W. Makinen - Chicago IL, US
Marta Zamora - Morris IL, US
Edward S. Foxley - Chicago IL, US
Assignee:
The University of Chicago - Chicago IL
International Classification:
A61K 49/06, C07F 9/00
Abstract:
A new, clinically applicable magnetic resonance imaging (MRI) method has been developed for in vivo imaging of a population of cells in a subject based on a class of paramagnetic divalent vanadyl-based contrast agents. The method includes administering to a subject a V-based contrast agent and monitoring distribution of the V-based contrast agent in the subject using magnetic resonance imaging.