MARVIN J SLEPIAN, MD
Osteopathic Medicine at Campbell Ave, Tucson, AZ

6443941, Sep 3, 2002

Jul 24, 2000

09/624055

Marvin J. Slepian - Tucson AZ
Anton Schindler - Durham NC

Endoluminal Therapeutics, Inc. - Tucson AZ

A61M 3100

604522, 60410103, 606108, 623 141

A novel process for paving or sealing the interior surface of a tissue lumen by entering the interior of the tissue lumen and applying a polymer to the interior surface of the tissue lumen. This is accomplished using a catheter which delivers the polymer to the tissue lumen and causes it to conform to the interior surface of lumen. The polymer can be delivered to the lumen as a monomer or prepolymer solution, or as an at least partially preformed layer on an expansible member.

6699272, Mar 2, 2004

Dec 13, 2001

10/020083

Marvin J. Slepian - Tucson AZ
Anton Schindler - Durham NC

Endoluminal Therapeutics, Inc.

A61E 206

623 111, 606108, 604113

A novel process for paving or sealing the interior surface of a tissue lumen by entering the interior of the tissue lumen and applying a polymer to the interior surface of the tissue lumen. This is accomplished using a catheter which delivers the polymer to the tissue lumen and causes it to conform to the interior surface of the lumen. The polymer can be delivered to the lumen as a monomer or prepolymer solution, or as an at least partially preformed layer on an expansile member.

6287320, Sep 11, 2001

Aug 26, 1997

8/918361

Marvin J. Slepian - Tucson AZ

Endoluminal Therapeutics, Inc. - Tucson AZ

A61M 2900

606194

The present invention provides a technique for treating diseased portions of tissue lumens by the focal introduction of at least one therapeutic agent at the diseased region. A catheter is positioned in a lumen such that first and second expansile members surround the diseased portion of tissue. The expansile members are expanded to occlude the diseased region and a therapeutic agent is introduced to the occluded diseased region via the catheter. The catheter is allowed to remain in place for a therapeutically effective period of time to allow the therapeutic agent to contact the diseased portion for such a period of time. The catheter arrangement also can be used to occlude a diseased region, remove physiological fluid from the occluded region and subsequently to disrupt the diseased region and/or apply the therapeutic agent. The therapeutic agent can be selected to suppress cell proliferation in the diseased region, and the occluded region can be treated with a medicament to promote vessel healing. The occluded region also can be paved with polymeric material.

2005019, Sep 1, 2005

Jan 28, 2005

11/046611

Janette Carpenter - Tucson AZ, US
Marvin Slepian - Tucson AZ, US

A61B001/32

600203000

A speculum sheath which covers a speculum and methods for using the sheath are described herein. A variety of different types of specula may be covered with the sheath, including anal, vaginal, ear, and nasal specula. The sheath is made of a compliant or partially compliant material, including latex, vinyl, natural and synthetic rubbers, silicone, nylon, polyethylene, polypropylene, and non-degradable or degradable elastomers. The material may be transparent or opaque. In the preferred embodiment, the material is transparent. The sheath may contain one or two openings. Optionally, the sheath contains an affixing means on the inside of or at least one of the openings on the sheath to prevent slippage when in contact with the speculum. Optionally, the sheath contains an active agent, such as hemostatic agents, anti-infectives, antibiotics, antimitotics anti-inflammatory, or other chemotherapeutic agents. In the preferred embodiment, the sheath is placed on a vaginal speculum and supports loose vaginal tissue when inserted into a patient. In the most preferred embodiment, the material is transparent so that medical provider may view the lumen.

2004002, Feb 5, 2004

Jul 31, 2003

10/631318

Marvin Slepian - Tucson AZ, US
Anton Schindler - Durham NC, US

Endoluminal Therapeutics, Inc. - Tucson AZ

A61F002/06, A61B017/00

606/214000, 623/001210

A novel process for paving or sealing the interior surface of a tissue lumen by entering the interior of the tissue lumen and applying a polymer to the interior surface of the tissue lumen. This is accomplished using a catheter which delivers the polymer to the tissue lumen and causes it to conform to the interior surface of the lumen. The polymer can be delivered to the lumen as a monomer or prepolymer solution, or as an at least partially preformed layer on an expansile member.

5749922, May 12, 1998

Jun 7, 1995

8/472757

Marvin J. Slepian - Tucson AZ
Anton Schindler - Durham NC

Endoluminal Therapeutics, Inc. - Tucson AZ

A61F 204, A61F 206

623 1

A novel process for paving or sealing the interior surface of a tissue lumen by entering the interior of the tissue lumen and applying a polymer to the interior surface of the tissue lumen. This is accomplished using a catheter which delivers the polymer to the tissue lumen and causes it to conform to the interior surface of lumen. The polymer can be delivered to the lumen as a monomer or prepolymer solution, or as an at least partially preformed layer on an expansile member.

5634946, Jun 3, 1997

Jun 7, 1995

8/474062

Marvin J. Slepian - Tucson AZ

Focal, Inc. - Lexington MA

A61F 206, A61F 204

623 11

A method for applying a paving material to a tissue surface is described. The method involves positioning a non-fluent polymeric material at the surface to be paved, rendering the material fluent, contacting the fluent polymer with the tissue surface, and allowing the polymer to return to its non-fluent condition.

5749915, May 12, 1998

Jun 7, 1995

8/481220

Marvin J. Slepian - Tucson AZ

Focal, Inc. - Lexington MA

A61F 204, A61F 206

623 1

A method for applying a paving material to a tissue surface is described. The method involves positioning a non-fluent polymeric material at the surface to be paved, rendering the material fluent, contacting the fluent polymer with the tissue surface, and allowing the polymer to return to its non-fluent condition.