MARTIN V CAMPBELL, JR
Electrician at Monticello Dr, Houston, TX
License number
Texas 69778
Expiration Date
Nov 4, 2017
Category
Journeyman Electrician
Address
Address
2707 Monticello Dr, Houston, TX 77045
Phone
(713) 305-1468
Professional information
Owner, Raw Electrical Services Llc
Position:
Owner at Raw Electrical Services LLC
Location:
Houston, Texas Area
Industry:
Construction
Work:
Raw Electrical Services LLC
-
Owner
Aa At Aaaaaaaaaa
Position:
aa at aaaaaaaaaa
Location:
Houston, Texas Area
Industry:
Computer Software
Work:
aaaaaaaaaa
-
aa
Controlled Modulation Of Amino Acid Side Chain Length Of Peptide Antigens
US Patent:
2005016, Aug 4, 2005
Filed:
Mar 6, 2003
Appl. No.:
10/507009
Inventors:
Constantin Ioannides - Houston TX, US
Martin Campbell - Houston TX, US
Catherine O'Brian - Houston TX, US
Martin Campbell - Houston TX, US
Catherine O'Brian - Houston TX, US
International Classification:
A61K039/00, A61K039/12, A61K039/02
US Classification:
424185100, 424186100, 424190100
Abstract:
The invention provides a method for the creation of peptide antigens comprising epitopes with at least a first modification comprising a shortened or lengthened amino acid side chain. By extension or shortening of the side chain with CH3/CH2 groups, for example, made by computer assisted modeling of the tumor antigen (peptide) bound in the MHC-I-groove, immunogenicity can be improved with minimal modification of adjacent tertiary structure, thereby avoiding cross-reactivity. Provided by the invention are methods of creating such antigens, as well as methods for therapeutic or prophylactic treatment of various conditions comprising administration of the antigens.