Inventors:
Bijan Almassian - Cheshire CT, US
Martin J. Sadowski - New York NY, US
Xu Kevin Lin - Branford CT, US
International Classification:
C07D 235/30, C07D 213/53, C07D 213/38
US Classification:
514357, 546334, 5483074, 514395
Abstract:
Compounds are provided according to formula I:where R, R′, R, R, R, and Rare as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, Alzheimer' s Disease, Down's syndrome, Parkinson's Disease, and others.