Inventors:
Linda O. Palladino - Stormville NY, US
Diana L. Clarke - Pittsburgh PA, US
Vivienne S. Marshall - Glenshaw PA, US
Charlotte A. Smith - Wexford PA, US
Martin C. Robson - Stuart FL, US
Assignee:
Stemnion, Inc. - Pittsburgh PA
International Classification:
C12N 5/02
Abstract:
The invention is directed to methods related to surgery, for example gastrointestinal surgery. In particular, the invention is methods of treating fistulae, promoting accelerated healing of anastomoses and preventing failure of anastomoses. Such methods utilize novel compositions, including but not limited to extraembryonic cytokine secreting cells (herein referred to as ECS cells), including, but not limited to, amnion-derived multipotent progenitor cells (herein referred to as AMP cells), conditioned media derived therefrom (herein referred to as amnion-derived cellular cytokine solution or ACCS), cell lysates derived therefrom, and cell products derived therefrom, each alone or in combination.