MARTHA JO MORRELL
Medical Practice in Menlo Park, CA
License number
Pennsylvania MD035763E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Menlo Park, CA 94025
Pennsylvania
Pennsylvania
Professional information
Treatment Of Language, Behavior And Social Disorders
US Patent:
2009032, Dec 31, 2009
Filed:
Sep 7, 2009
Appl. No.:
12/554954
Inventors:
Martha J. Morrell - Atherton CA, US
International Classification:
A61N 1/36
US Classification:
607 45
Abstract:
Methods of treating language, behavioral and social disorders are described, including methods of treating language disorders associated with electrographic abnormalities in the primary or associative language cortex of persons with autism spectrum disorders, pervasive developmental delay or acquired epileptic aphasia. A language, behavioral and social disorder may be treated by detecting epileptiform activity or an electrographic seizure for a subject's brain and applying neurostimulation to a language cortical region of the subject's brain (e.g., a primary or associative language cortical region). Detection of epileptiform activity or an electrographic seizure and stimulation of language cortex may be performed by a sensing and/or stimulation electrode that is inserted into a subject's brain and connected to one or more neurostimulation devices for monitoring and/or stimulating the language cortex.
Treatment Of Language, Behavior And Social Disorders
US Patent:
2008007, Mar 27, 2008
Filed:
Sep 21, 2006
Appl. No.:
11/525586
Inventors:
Martha J. Morrell - Atherton CA, US
International Classification:
A61N 1/00
US Classification:
607 45
Abstract:
Methods of treating language, behavioral and social disorders are described, including methods of treating language disorders associated with electrographic abnormalities in the primary or associative language cortex of persons with autism spectrum disorders, pervasive developmental delay or acquired epileptic aphasia. A language, behavioral and social disorder may be treated by detecting epileptiform activity or an electrographic seizure for a subject's brain and applying neurostimulation to a language cortical region of the subject's brain (e.g., a primary or associative language cortical region). Detection of epileptiform activity or an electrographic seizure and stimulation of language cortex may be performed by a sensing and/or stimulation electrode that is inserted into a subject's brain and connected to one or more neurostimulation devices for monitoring and/or stimulating the language cortex.
Drug Eluting Lead Systems
US Patent:
2011000, Jan 6, 2011
Filed:
Aug 30, 2010
Appl. No.:
12/871865
Inventors:
C. Lance Boling - San Jose CA, US
Daniel Chao - San Francisco CA, US
Martha J. Morrell - Portola Valley CA, US
Benjamin D. Pless - Atherton CA, US
Thomas K. Tcheng - Pleasant Hill CA, US
Brett M. Wingeier - San Francisco CA, US
Daniel Chao - San Francisco CA, US
Martha J. Morrell - Portola Valley CA, US
Benjamin D. Pless - Atherton CA, US
Thomas K. Tcheng - Pleasant Hill CA, US
Brett M. Wingeier - San Francisco CA, US
Assignee:
NEUROPACE, INC. - Mountain View CA
International Classification:
A61N 1/05
US Classification:
607116
Abstract:
Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e.g., by a substantial portion of the area of the substrate). Examples of bioactive agents that may be used in the lead system include bioactive agents that promote neural adhesion and living cells that have been biologically manipulated, engineered cells, and cells of a particular phenotype and/or adapted to induce a desired neural or glial response. Methods described herein may comprise contacting the substrate of a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.
Refillable Reservoir Lead Systems
US Patent:
8190270, May 29, 2012
Filed:
Jan 10, 2012
Appl. No.:
13/347675
Inventors:
Brett M. Wingeier - San Francisco CA, US
Martha Morrell - Portola Valley CA, US
Carl Lance Boling - San Jose CA, US
Martha Morrell - Portola Valley CA, US
Carl Lance Boling - San Jose CA, US
Assignee:
NeuroPace, Inc. - Mountain View CA
International Classification:
A61N 1/00
US Classification:
607116
Abstract:
Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.
Refillable Reservoir Lead Systems
US Patent:
8160720, Apr 17, 2012
Filed:
Sep 13, 2010
Appl. No.:
12/881171
Inventors:
Brett M. Wingeier - San Francisco CA, US
Martha Morrell - Portola Valley CA, US
Carl Lance Boling - San Jose CA, US
Martha Morrell - Portola Valley CA, US
Carl Lance Boling - San Jose CA, US
Assignee:
NeuroPace, Inc. - Mountain View CA
International Classification:
A61N 1/00
US Classification:
607116
Abstract:
Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.
Drug Eluting Lead Systems
US Patent:
7844345, Nov 30, 2010
Filed:
Feb 8, 2007
Appl. No.:
11/704549
Inventors:
C. Lance Boling - San Jose CA, US
Daniel Chao - San Francisco CA, US
Martha J. Morrell - Atherton CA, US
Benjamin D. Pless - Mountain View CA, US
Thomas K. Tcheng - Pleasant Hill CA, US
Brett M. Wingeier - San Francisco CA, US
Daniel Chao - San Francisco CA, US
Martha J. Morrell - Atherton CA, US
Benjamin D. Pless - Mountain View CA, US
Thomas K. Tcheng - Pleasant Hill CA, US
Brett M. Wingeier - San Francisco CA, US
Assignee:
NeuroPace, Inc. - Mountain View CA
International Classification:
A61N 1/00
US Classification:
607116
Abstract:
Medical electrical lead systems and related methods are described. The lead systems may be configured to be at least partially implanted in neural tissue of a subject, such as a brain of a subject. Some variations of the lead systems may comprise a lead body, an electrode connected to the lead body, and a bioactive agent. The electrode and/or lead body may comprise a substrate, and the bioactive agent may be supported by the substrate (e. g. , by a substantial portion of the area of the substrate). Examples of bioactive agents that may be used in the lead system include antiproliferative agents, bactericidal agents, bacteriostatic agents, antiepileptic agents, and/or antifungal agents. Methods described herein may comprise coating a lead body and/or an electrode of a medical electrical lead system with at least one bioactive agent, where the lead body and the electrode are connected to each other.
Responsive Therapy For Psychiatric Disorders
US Patent:
2008012, May 29, 2008
Filed:
Feb 8, 2008
Appl. No.:
12/028699
Inventors:
Martha Morrell - Portola Valley CA, US
Assignee:
NEUROPACE, INC. - Mountain View CA
International Classification:
A61N 1/05
US Classification:
607 45
Abstract:
A medical device is capable of delivering a form of stimulation (e.g., electrical stimulation) to a region of the cingulate cortex of the human brain to treat a neurological event, condition or disorder, especially an event, condition, or disorder that is psychiatric in nature, such as depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders. The device additionally or alternatively may be capable of detecting a biological marker or changes in a biological marker corresponding to the neurological event, condition or disorder. Methods of using the device are also disclosed.
Refillable Reservoir Lead Systems
US Patent:
7813811, Oct 12, 2010
Filed:
Feb 8, 2007
Appl. No.:
11/704534
Inventors:
Brett M. Wingeier - San Francisco CA, US
Martha J. Morrell - Atherton CA, US
C. Lance Boling - San Jose CA, US
Martha J. Morrell - Atherton CA, US
C. Lance Boling - San Jose CA, US
Assignee:
NeuroPace, Inc. - Mountain View CA
International Classification:
A61N 1/00
US Classification:
607116
Abstract:
Medical electrical lead systems and related methods are described. The medical electrical lead systems may be configured to be at least partially implanted in a body of a subject. Some variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and a lumen extending at least partially therebetween, at least one electrode in the proximity of the distal end of the lead body, and a reservoir in fluid communication with the lumen, where the reservoir is located at a position removed from the distal end of the lead body. Certain variations of the medical electrical lead systems may comprise a lead body comprising a proximal end and a distal end and first and second lumens extending at least partially therebetween, and at least one electrode in the proximity of the distal end of the lead body.
Responsive Therapy For Psychiatric Disorders
US Patent:
2008012, May 29, 2008
Filed:
Feb 8, 2008
Appl. No.:
12/028625
Inventors:
Martha Morrell - Portola Valley CA, US
Assignee:
NEUROPACE, INC. - Mountain View CA
International Classification:
A61N 1/05
US Classification:
607 45
Abstract:
An implantable medical device is capable of delivering a form of therapy (e.g., electrical stimulation) to a region of the cingulate cortex of a patient's brain to treat a neurological event, condition or disorder, especially an event, condition, or disorder that is psychiatric in nature, such as depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders. The apparatus is also capable of detecting a signal corresponding to a characteristic of the psychiatric disorder. Methods of using the apparatus are also disclosed.
Responsive Therapy For Psychiatric Disorders
US Patent:
2006005, Mar 16, 2006
Filed:
Sep 14, 2004
Appl. No.:
10/941759
Inventors:
Martha Morrell - Portola Valley CA, US
Assignee:
NeuroPace, Inc. - Mountain View CA
International Classification:
A61N 1/34
US Classification:
607046000
Abstract:
An implantable neurostimulator system for treating psychiatric disorders includes scheduled and responsive therapy capabilities including responsive stimulation applied to the cingulate gyrus of the brain. Methods for treating depression, bipolar disorder, anxiety and obsessive-compulsive disorders, post-traumatic stress disorder, addiction, schizophrenia, and autism and other developmental disorders employ an inventive system to advantageously reduce symptoms and address underlying causes of the disorders.