Inventors:
Nicolaas M. J. Vermeulin - Woodinville WA 98072
Christine L. ODay - Mountlake Terrace WA 98043
Heather K. Webb - Seattle WA 98107
Mark R. Burns - Shoreline WA 98177
Donald E. Bergstrom - West Lafayette IN 47906
International Classification:
C07C27112
US Classification:
560 25, 549 65, 549560, 564 83, 564 84, 564215, 514269, 514270, 514290, 514299, 514354, 514361, 514378, 514445, 514468, 514478, 514520, 514561, 514602, 514616, 514629, 514673, 514674, 544300, 546101, 546152, 548127, 548248, 548537, 558411
Abstract:
Novel âbispolyamineâ inhibitor compounds of polyamine transport are disclosed. These compounds are useful pharmaceutical agents for treating diseases where it is desired to inhibit polyamine transport or other polyamine binding proteins, for example cancer and post-angioplasty injury. These compounds display desirable activities both for diagnostic and research assays and therapy.