MARK S RIENSTRA
Engineers in Lansdale, PA
License number
Pennsylvania PE035318E
Category
Engineers
Type
Professional Engineer
Address
Address
Lansdale, PA 19446
Professional information
Mark Rienstra - Lansdale, PA
Work:
Nuron Biotech
Senior Director Manufacturing Operations West Pharmaceutical Systems - Lionville, PA
Associate Director Quality Assurance Teva Pharmaceuticals - N. Wales, PA, US
Associate Director, Global Project Coordination Merck and Co., Inc - West Pt, PA, US
Manager, Sterile Process Technology Merck and Co., Inc
Validation Manager, Sterile Process Technology Merck and Co
Senior Sterile Process Engineer, Sterile Process Technology Merck and Co - West Pt, PA, US
Senior Biochemical Engineer, Sterile Process Engineering
Senior Director Manufacturing Operations West Pharmaceutical Systems - Lionville, PA
Associate Director Quality Assurance Teva Pharmaceuticals - N. Wales, PA, US
Associate Director, Global Project Coordination Merck and Co., Inc - West Pt, PA, US
Manager, Sterile Process Technology Merck and Co., Inc
Validation Manager, Sterile Process Technology Merck and Co
Senior Sterile Process Engineer, Sterile Process Technology Merck and Co - West Pt, PA, US
Senior Biochemical Engineer, Sterile Process Engineering
Education:
U. of Michigan - Ann Arbor, MI
BS in Chemical Engineering Calvin College - Grand Rapids, MI
BS in Engineering and Letters
BS in Chemical Engineering Calvin College - Grand Rapids, MI
BS in Engineering and Letters
Mark Rienstra - Lansdale, PA
Work:
Nuron Biotech - Exton, PA
Senior Director Manufacturing Operations West Pharmaceutical Systems - Lionville, PA
Associate Director Global Quality Assurance Teva Pharmaceuticals - N. Wales, PA, US
Associate Director, Global Project Coordination Merck and Co., Inc - West Pt, PA, US
Manager Validation, Sterile Process Technology
Senior Director Manufacturing Operations West Pharmaceutical Systems - Lionville, PA
Associate Director Global Quality Assurance Teva Pharmaceuticals - N. Wales, PA, US
Associate Director, Global Project Coordination Merck and Co., Inc - West Pt, PA, US
Manager Validation, Sterile Process Technology
Education:
U. of Michigan - Ann Arbor, MI
BS in Chemical Engineering Bio Emphasis Calvin College - Grand Rapids, MI
BS in Engineering and Letters
BS in Chemical Engineering Bio Emphasis Calvin College - Grand Rapids, MI
BS in Engineering and Letters
Process For Removing Bacterial Endotoxin From Gram-Negative Polysaccharides
US Patent:
5039610, Aug 13, 1991
Filed:
Oct 9, 1990
Appl. No.:
7/595737
Inventors:
Mark S. Rienstra - Lansdale PA
Edgar M. Scattergood - Lansdale PA
Robert D. Sitrin - Lafayette Hill PA
Edgar M. Scattergood - Lansdale PA
Robert D. Sitrin - Lafayette Hill PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P, C12P, C12P 104, C12R 121
US Classification:
435101
Abstract:
A process for removing endotoxin from Gram-negative polysaccharides such as polyribosylribitol phosphate by solubilizing polysaccharide-containing powder derived from Gram-negative bacteria fermentation broth to provide a divalent counter ion for endotoxin and adding alcohol incrementally to induce lipopolysaccharide precipition, and mixing material resulting from the alcohol addition with a nonionic resin, a detergent and a chelating agent.
Disposable Storage, Transport And Resuspension System
US Patent:
6071005, Jun 6, 2000
Filed:
Jun 11, 1997
Appl. No.:
8/873095
Inventors:
Anand Ekambaram - Brookhaven PA
Wendy L. Radcliff - Souderton PA
Mark S. Rienstra - Lansdale PA
Brett L. Allred - Hyde Park UT
Doyle W. Stewart - Hyrum UT
Wendy L. Radcliff - Souderton PA
Mark S. Rienstra - Lansdale PA
Brett L. Allred - Hyde Park UT
Doyle W. Stewart - Hyrum UT
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61B 1900
US Classification:
3661732
Abstract:
The present invention relates to a package for storing, mixing, resuspending and dispensing sterile or non-sterile solutions or suspensions and comprises a sterilizable bag having fittings which provide for the introduction and exit of fluids and solids, as well as means for resuspending and stirring the fluids. Additionally, structural support means are provided for shipment, filling and dispensing. Unlike conventional stainless steel equipment, the system is disposable, does not require cleaning, provides for safe, rapid and accurate resuspension of suspended solids and can accommodate a wide range of liquid volumes.
Process For Removing Bacterial Endotoxin From Gram-Negative Polysaccharides
US Patent:
5019502, May 28, 1991
Filed:
Oct 3, 1990
Appl. No.:
7/593535
Inventors:
Mark S. Rienstra - Lansdale PA
Edgar M. Scattergood - Lansdale PA
Edgar M. Scattergood - Lansdale PA
Assignee:
Merck & Company, Inc. - Rahway NJ
International Classification:
C12P 104, C12P 1904, C12R 121
US Classification:
435101
Abstract:
A process for removing endotoxin from Gram-negative polysaccharides such as H. influenzae polyribosylribitol phosphate by mixing with a nonionic resin, a detergent and a chelating agent.
Process For Converting Lipid-Containing Bacterial Capsular Polysaccharide Into Lipid-Free Polysaccharide
US Patent:
5314811, May 24, 1994
Filed:
Jul 13, 1992
Appl. No.:
7/909346
Inventors:
Ann L. Lee - Lansdale PA
Mark S. Rienstra - Lansdale PA
Walter E. Manger - Harleysville PA
Robert D. Sitrin - Lafayette Hill PA
Mark S. Rienstra - Lansdale PA
Walter E. Manger - Harleysville PA
Robert D. Sitrin - Lafayette Hill PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1904, C12P 104, C12R 121
US Classification:
435101
Abstract:
A process for converting lipid-containing bacterial capsular polysaccharide, such as lipo-polyribosyl ribitol phosphate, lipo-PRP, into lipid-free, endotoxin-free polysaccharide, such as polyribosyl ribitol phosphate, PRP, by solubilizing polysaccharide-containing powder derived from culture media of bacteria, such as Haemophilus influenzae type b, cleaving covalently bound fatty acids from the polysaccharide, and removing the lipids, and endotoxin.
Process For Removing Bacterial Endotoxin From Gram-Negative Polysaccharides
US Patent:
5045456, Sep 3, 1991
Filed:
Oct 9, 1990
Appl. No.:
7/595722
Inventors:
Mark S. Rienstra - Lansdale PA
Edgar M. Scattergood - Lansdale PA
Edgar M. Scattergood - Lansdale PA
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C12P 1904, C12P 104, C12R 121
US Classification:
435101
Abstract:
A process for removing endotoxin from Gram-negative polysaccharides such as H. influenzae polyribosylribitol phosphate by adding alcohol incrementally until substantially all lipopolysaccharide precipitates.