Inventors:
Mark A. Rubin - Newton MA, US
Arul M. Chinnaiyan - Plymouth MI, US
Bharathi Laxman - Ann Arbor MI, US
Arun Sreekumar - Ann Arbor MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
G01N 33/53
US Classification:
435 71, 435 6, 435 74, 435960, 436501, 436512, 436536, 436 64, 436813
Abstract:
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression profiles associated with prostate cancers. The present invention also provides novel markers useful for the diagnosis, characterization, and treatment of prostate cancers. In particular, the present invention provides methods and compositions for the detection of α-methylacyl-CoA racemase (AMACR) in the urine as a marker for prostate cancer detection.