MARK ERIC JOSEPHSON
Medical Practice in Brookline, MA

License number
Pennsylvania MD015562E
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address 2
Brookline, MA 02146
Pennsylvania

Professional information

Mark Josephson Photo 1

Differentiating Ischemic From Non-Ischemic T-Wave Inversion

US Patent:
7925336, Apr 12, 2011
Filed:
Oct 2, 2009
Appl. No.:
12/572747
Inventors:
Alexei V. Shvilkin - Chestnut Hill MA, US
Mark E. Josephson - Brookline MA, US
Assignee:
Beth Israel Deaconess Medical Center - Boston MA
International Classification:
A61B 5/0452
US Classification:
600517
Abstract:
A method of discriminating between ischemic and cardiac memory effects in a heart, comprising receiving electrocardiographic (ECG) data, calculating, from the ECG data, a direction of a T-wave vector, diagnosing ischemia if the T-wave vector is between about 75 degrees and about 200 degrees, and diagnosing cardiac memory if the T-wave vector is between about zero degrees and minus 90 degrees. Also presented is a system for discriminating between ischemic and cardiac memory effects in a heart comprising means for performing an electrocardiogram, means for calculating a direction of a T-wave vector, means for diagnosing ischemia if the T-wave vector is between about 90 degrees and 180 degrees, and means for diagnosing cardiac memory if the T-wave vector is between about zero degrees and minus 90 degrees.


Mark Josephson Photo 2

Differentiating Ischemic From Non-Ischemic T-Wave Inversion

US Patent:
7620449, Nov 17, 2009
Filed:
Jan 22, 2007
Appl. No.:
11/625538
Inventors:
Alexei V. Shvilkin - Chestnut Hill MA, US
Mark E. Josephson - Brookline MA, US
Assignee:
Beth Israel Deaconess Medical Center - Boston MA
International Classification:
A61B 5/0452
US Classification:
600517, 600512
Abstract:
A method of discriminating between ischemic and cardiac memory effects in a heart, comprising receiving electrocardiographic (ECG) data, calculating, from the ECG data, a direction of a T-wave vector, diagnosing ischemia if the T-wave vector is between about 75 degrees and about 200 degrees, and diagnosing cardiac memory if the T-wave vector is between about zero degrees and minus 90 degrees. Also presented is a system for discriminating between ischemic and cardiac memory effects in a heart comprising means for performing an electrocardiogram, means for calculating a direction of a T-wave vector, means for diagnosing ischemia if the T-wave vector is between about 90 degrees and 180 degrees, and means for diagnosing cardiac memory if the T-wave vector is between about zero degrees and minus 90 degrees.


Mark Josephson Photo 3

Differentiating Ischemic From Non-Ischemic T-Wave Inversion

US Patent:
7194299, Mar 20, 2007
Filed:
May 21, 2004
Appl. No.:
10/849879
Inventors:
Alexei V. Shvilkin - Chestnut Hill MA, US
Mark E. Josephson - Brookline MA, US
Assignee:
Beth Israel Deaconess Medical Center - Boston MA
International Classification:
A61B 5/0452
US Classification:
600517
Abstract:
A method of differentiating between ischemic and cardiac memory inverted T-waves includes performing an electrocardiogram of a patient; identifying inverted T-waves in at least some of precordial leads; identifying T-waves in leads I and aVL; diagnosing ischemia if leads I and aVL show inverted T-waves; and diagnosing cardiac memory if the leads I and aVL show non-inverted T-waves. The method may also include identifying T-waves in lead III; confirming ischemic diagnosis if the lead III shows deeper inverted T-waves than in the precordial leads; and confirming cardiac memory diagnosis otherwise.