MARK E BOLANDER, M.D.
Medical Practice at 1 St, Rochester, MN
License number
Minnesota 34372
Category
Medical Practice
Type
Orthopaedic Surgery
Address
Address
200 1St St SW, Rochester, MN 55905
Phone
(507) 284-2511
Professional information
Site-Directed Transfection With Ultrasound And Cavitation Nuclei
US Patent:
2001005, Dec 20, 2001
Filed:
Jul 2, 1998
Appl. No.:
09/110049
Inventors:
JAMES F. GREENLEAF - ROCHESTER MN, US
MARK E. BOLANDER - ROCHESTER MN, US
WILLIAM J. GREENLEAF - ROCHESTER MN, US
MARK E. BOLANDER - ROCHESTER MN, US
WILLIAM J. GREENLEAF - ROCHESTER MN, US
International Classification:
A61N001/18, A61H005/00, A61N001/38
US Classification:
424/450000, 204/157150, 600/455000, 600/468000, 600/434000, 600/458000, 601/002000, 606/028000, 607/024000
Abstract:
A method for the delivery of substances to a cell is disclosed. In a preferred embodiment, one administers continuous wave ultrasound or pulse-wave ultrasound to a cell bathed in a cocktail containing macromolecules and monitors the ultrasound using reflected echos of the ultrasound. One then observes incorporation of the substances into the cell. In a preferred embodiment of the present invention, macromolecules are combined in a cocktail solution comprising bubble micronuclei.
Site-Directed Transfection With Ultrasound And Cavitation Nuclei
US Patent:
2003007, Apr 24, 2003
Filed:
Jul 11, 2002
Appl. No.:
10/193637
Inventors:
James Greenleaf - Rochester MN, US
Mark Bolander - Rochester MN, US
William Greenleaf - Rochester MN, US
Mark Bolander - Rochester MN, US
William Greenleaf - Rochester MN, US
International Classification:
A61K048/00, C12N015/85, A61N001/30
US Classification:
514/044000, 604/020000, 435/455000
Abstract:
A method for the delivery of substances to a cell is disclosed. In a preferred embodiment, one administers continuous wave ultrasound or pulse-wave ultrasound to a cell bathed in a cocktail containing macromolecules and monitors the ultrasound using reflected echoes of the ultrasound. One then observes incorporation of the substances into the cell. In a preferred embodiment of the present invention, macromolecules are combined in a cocktail solution comprising bubble micronuclei.
Mark Edward Bolander, Rochester MN
Specialties:
Orthopaedic Surgery
Work:
Mayo Medical School
200 1St St SW, Rochester, MN 55905
200 1St St SW, Rochester, MN 55905
Education:
Loyola University Chicago (1979)
Mark E Bolander, Rochester MN
Specialties:
Orthopedic Surgeon
Address:
200 1St St Sw, Rochester, MN 55905
Education:
Doctor of Medicine
Board certifications:
American Board of Orthopaedic Surgery Certification in Orthopaedic Surgery
Dr. Mark E Bolander, Rochester MN - MD (Doctor of Medicine)
Specialties:
Orthopedic Surgery
Address:
Mayo Clinic
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
200 1St St SW, Rochester 55905
(507) 284-2511 (Phone)
Certifications:
Orthopedic Surgery, 2004
Awards:
Healthgrades Honor Roll
Languages:
English
Education:
Medical School
Loyola University Of Chicago/Stritch School Of Medicine
Graduated: 1979
University Of Mi Hosps and Health Ctrs
Northwestern University
Graduated: 1975
Loyola University Of Chicago/Stritch School Of Medicine
Graduated: 1979
University Of Mi Hosps and Health Ctrs
Northwestern University
Graduated: 1975
Methods For Amplifying Nucleic Acid Sequences
US Patent:
6562572, May 13, 2003
Filed:
Sep 27, 2000
Appl. No.:
09/671043
Inventors:
Gobinda Sarkar - Rochester MN
Mark E. Bolander - Rochester MN
Mark E. Bolander - Rochester MN
Assignee:
Mayo Foundation for Medical Education and Research - Rochester MN
International Classification:
C12Q 168
US Classification:
435 6, 435 691, 435 9121, 536 221, 536 2433
Abstract:
Methods for identifying differentially expressed mRNA molecules are described, as well as methods for amplifying nucleic acid sequences.
Transport Of Biologically Active Molecules Into A Cell, Mitochondrion, Or Nucleus
US Patent:
2010011, May 13, 2010
Filed:
Jan 15, 2009
Appl. No.:
12/354142
Inventors:
Gobinda Sarkar - Rochester MN, US
Mark E. Bolander - Rochester MN, US
Deendayal Mandal - Kingston RI, US
Eric W. Mahlum - Rochester MN, US
Michael J. Yaszemski - Rochester MN, US
Mark E. Bolander - Rochester MN, US
Deendayal Mandal - Kingston RI, US
Eric W. Mahlum - Rochester MN, US
Michael J. Yaszemski - Rochester MN, US
International Classification:
A61K 39/395, C07K 14/00, C07K 7/08, C07K 9/00, C07K 16/00, A61K 38/16, A61K 38/10, A61K 38/14, A61K 39/385, C12N 5/00, C12N 15/00, A61P 43/00
US Classification:
4241781, 530324, 530326, 530325, 530322, 5303911, 514 12, 514 13, 514 8, 4241931, 435375, 435440
Abstract:
Novel carrier peptides are described, as well as methods of using the carrier peptides to transport biologically active molecules into a cell, mitochondrion, or nucleus, e.g., by formation of a complex of the carrier peptide non-covalently bound to a biologically active molecule.
Sonic Activation Of Strain Sensitive Cells
US Patent:
2006023, Oct 26, 2006
Filed:
Feb 13, 2006
Appl. No.:
11/352875
Inventors:
James Greenleaf - Rochester MN, US
Mark Bolander - Rochester MN, US
Heather Argadine - Rochester MN, US
Randall Kinnick - Rochester MN, US
Mark Bolander - Rochester MN, US
Heather Argadine - Rochester MN, US
Randall Kinnick - Rochester MN, US
International Classification:
G01V 13/00
US Classification:
073001820
Abstract:
A method and apparatus for stimulating the growth of chondrocytes as part of a bone healing process includes a loudspeaker that applies audio frequency acoustic energy to the cells. A 1 kHz square wave at a 20 percent duty cycle is used and it is applied for a period of 20 minutes on each of a series of consecutive day.