MARK DAVID MCDONNELL
Nursing in Lansdale, PA
License number
Pennsylvania TGPN013283
Category
Nursing
Type
Graduate Practical Nurse Permit
Address
Address
Lansdale, PA 19446
Personal information
See more information about MARK DAVID MCDONNELL at radaris.comName
Address
Phone
608 Garber St, Hollidaysburg, PA 16648
4522 Tyson Ave, Philadelphia, PA 19135
3539 State Route 106, Clifford Township, PA 18470
4227 Vista St, Philadelphia, PA 19136
4217 Lackland Pl, Philadelphia, PA 19114
Professional information
Aminotetralin-Derived Urea Modulators Of Vanilloid Vr1 Receptor
US Patent:
8569505, Oct 29, 2013
Filed:
Jan 22, 2010
Appl. No.:
12/692128
Inventors:
Ellen Codd - Blue Bell PA, US
Scott L. Dax - Landenberg PA, US
Michele Jetter - Norristown PA, US
Mark McDonnell - Lansdale PA, US
James J. McNally - Souderton PA, US
Mark Youngman - Warminster PA, US
Scott L. Dax - Landenberg PA, US
Michele Jetter - Norristown PA, US
Mark McDonnell - Lansdale PA, US
James J. McNally - Souderton PA, US
Mark Youngman - Warminster PA, US
Assignee:
Janssen Pharmaceutica, NV
International Classification:
C07D 217/02, C07C 275/28
US Classification:
546139, 546143, 546146, 546159, 546176, 564 26, 564 47, 564 48
Abstract:
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
Piperidin-4-Yl-Azetidine Diamides As Monoacylglcerol Lipase Inhibitors
US Patent:
2013024, Sep 19, 2013
Filed:
May 2, 2013
Appl. No.:
13/875430
Inventors:
- Beerse, BE
Haiyan Bian - Princeton NJ, US
Xun Li - New Hope NJ, US
Li Liu - Germantown MD, US
Mark J. Macielag - Gwynedd Valley PA, US
Mark E. McDonnell - Lansdale PA, US
Haiyan Bian - Princeton NJ, US
Xun Li - New Hope NJ, US
Li Liu - Germantown MD, US
Mark J. Macielag - Gwynedd Valley PA, US
Mark E. McDonnell - Lansdale PA, US
Assignee:
Janssen Pharmaceutica, NV - Beerse
International Classification:
C07D 417/14
US Classification:
51421018, 546202, 546209, 546201, 546199
Abstract:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds, and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, are represented by Formula (I) as follows:wherein Y, Z, and R are defined herein.
Aminotetralin-Derived Urea Modulators Of Vanilloid Vr1 Receptor
US Patent:
7678812, Mar 16, 2010
Filed:
Oct 23, 2007
Appl. No.:
11/877220
Inventors:
Ellen Codd - Blue Bell PA, US
Scott L. Dax - Landenberg PA, US
Michele Jetter - Norristown PA, US
Mark McDonnell - Lansdale PA, US
James J. McNally - Souderton PA, US
Mark Youngman - Warminster PA, US
Scott L. Dax - Landenberg PA, US
Michele Jetter - Norristown PA, US
Mark McDonnell - Lansdale PA, US
James J. McNally - Souderton PA, US
Mark Youngman - Warminster PA, US
Assignee:
Janssen Pharmaceutica NV
International Classification:
A61K 31/47, C07D 211/06, C07D 217/22
US Classification:
514307, 514311, 514314, 514357, 514396, 514595, 514596, 546139, 546143, 546159, 546176, 564 26, 564 47, 564 48
Abstract:
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to β-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
Tricyclic-Bridged Piperidinylidene Derivatives As Delta Opioid Modulators
US Patent:
2009029, Nov 26, 2009
Filed:
May 22, 2009
Appl. No.:
12/470675
Inventors:
Scott Dax - Landenberg PA, US
Bart DeCorte - Southhampton PA, US
Li Liu - Doylestown PA, US
Mark McDonnell - Lansdale PA, US
James McNally - Souderton PA, US
Bart DeCorte - Southhampton PA, US
Li Liu - Doylestown PA, US
Mark McDonnell - Lansdale PA, US
James McNally - Souderton PA, US
International Classification:
A61K 31/44, C07D 405/04, C07D 409/04, C07D 405/14, C07D 413/14, C07D 415/00, C07D 409/14
US Classification:
514304, 546126
Abstract:
Disclosed are compounds, compositions and methods for treating various diseases and conditions, including pain. Such compounds are represented by Formula I as follows:
Azetidinyl Diamides As Monoacylglycerol Lipase Inhibitors
US Patent:
8604017, Dec 10, 2013
Filed:
Dec 17, 2012
Appl. No.:
13/716705
Inventors:
Kristen Chevalier - Collegeville PA, US
Jose Clemente - West Chester PA, US
Pete Connolly - Spring House PA, US
Chris Flores - Spring House PA, US
Shu-Chen Lin - Doylestown PA, US
Li Liu - Germantown MD, US
John Mabus - East Greenville PA, US
Mark Macielag - Spring House PA, US
Mark McDonnell - Lansdale PA, US
Philip Pitis - North Wales PA, US
Yue-Mei Zhang - Spring House PA, US
Sui-Po Zhang - Malvern PA, US
Bin Zhu - Spring House PA, US
Jose Clemente - West Chester PA, US
Pete Connolly - Spring House PA, US
Chris Flores - Spring House PA, US
Shu-Chen Lin - Doylestown PA, US
Li Liu - Germantown MD, US
John Mabus - East Greenville PA, US
Mark Macielag - Spring House PA, US
Mark McDonnell - Lansdale PA, US
Philip Pitis - North Wales PA, US
Yue-Mei Zhang - Spring House PA, US
Sui-Po Zhang - Malvern PA, US
Bin Zhu - Spring House PA, US
Assignee:
Janssen Pharmaceutica NV - Beerse
International Classification:
A61K 31/496, C07D 403/06, C07D 409/06
US Classification:
51421018, 544359, 544371, 544373, 544376
Abstract:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows:.
Tricyclic Opioid Modulators
US Patent:
2009027, Nov 5, 2009
Filed:
Jul 10, 2009
Appl. No.:
12/500706
Inventors:
Bart DeCorte - Southampton PA, US
Li Liu - Doylestown PA, US
Mark McDonnell - Lansdale PA, US
Jim McNally - Souderton PA, US
Li Liu - Doylestown PA, US
Mark McDonnell - Lansdale PA, US
Jim McNally - Souderton PA, US
International Classification:
A61K 31/4725, C07D 405/14, A61K 31/403, A61K 31/4439, A61P 25/00
US Classification:
514310, 548454, 514414, 514339, 5462767, 546143
Abstract:
The invention is directed to compounds of Formula (I) useful as delta and mu opioid receptor modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
Labeled Resiniferatoxin Derivatives
US Patent:
7112685, Sep 26, 2006
Filed:
Oct 9, 2001
Appl. No.:
09/973378
Inventors:
Mark E. McDonnell - Lansdale PA, US
Larry E. Weaner - Palmyra NJ, US
Sui Po Zhang - Bala Cynwyd PA, US
Larry E. Weaner - Palmyra NJ, US
Sui Po Zhang - Bala Cynwyd PA, US
Assignee:
Ortho-McNeil Pharmaceutical, Inc. - Raritan NJ
International Classification:
C07D 321/10, C07D 321/12
US Classification:
549348, 549349
Abstract:
This invention relates resiniferatoxin derivatives useful in a vanilloid receptor binding assay and methods for production thereof.
Azetidinyl Diamides As Monoacylglycerol Lipase Inhibitors
US Patent:
8399454, Mar 19, 2013
Filed:
Apr 22, 2010
Appl. No.:
12/765254
Inventors:
Haiyan Bian - Princeton NJ, US
Kristen Chevalier - Collegeville PA, US
Jose Clemente - Spring House PA, US
Pete Connolly - Spring House PA, US
Chris Flores - Springhouse PA, US
Shu-Chen Lin - Doylestown PA, US
Li Liu - Doylestown PA, US
John Mabus - East Greenville PA, US
Mark Macielag - Spring House PA, US
Mark McDonnell - Lansdale PA, US
Philip Pitis - No. Wales PA, US
Yue-Mei Zhang - Springhouse PA, US
Sui-Po Zhang - Radnor PA, US
Bin Zhu - Spring House PA, US
Kristen Chevalier - Collegeville PA, US
Jose Clemente - Spring House PA, US
Pete Connolly - Spring House PA, US
Chris Flores - Springhouse PA, US
Shu-Chen Lin - Doylestown PA, US
Li Liu - Doylestown PA, US
John Mabus - East Greenville PA, US
Mark Macielag - Spring House PA, US
Mark McDonnell - Lansdale PA, US
Philip Pitis - No. Wales PA, US
Yue-Mei Zhang - Springhouse PA, US
Sui-Po Zhang - Radnor PA, US
Bin Zhu - Spring House PA, US
Assignee:
Janssen Pharmaceutica, NV
International Classification:
A61K 31/496, A61K 31/55, A61K 31/5377, C07D 205/04, C07D 295/12, C07D 401/12, C07D 403/04, C07D 409/06, C07D 413/12
US Classification:
51421705, 5142358, 51425213, 51425301, 51425306, 51425312, 51425402, 51425406, 51425409, 540598, 544121, 544359, 544360, 544363, 544368, 544370, 544372, 544376
Abstract:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows:.
Azetidinyl Diamides As Monoacylglycerol Lipase Inhibitors
US Patent:
8623858, Jan 7, 2014
Filed:
Dec 18, 2012
Appl. No.:
13/718257
Inventors:
Kristen Chevalier - Collegeville PA, US
Jose Clemente - West Chester PA, US
Pete Connolly - Spring House PA, US
Chris Flores - Spring House PA, US
Shu-Chen Lin - Doylestown PA, US
Li Liu - Germantown MD, US
John Mabus - East Greenville PA, US
Mark Macielag - Spring House PA, US
Mark McDonnell - Lansdale PA, US
Philip Pitis - North Wales PA, US
Yue-Mei Zhang - Spring House PA, US
Sui-Po Zhang - Malvern PA, US
Bin Zhu - Spring House PA, US
Jose Clemente - West Chester PA, US
Pete Connolly - Spring House PA, US
Chris Flores - Spring House PA, US
Shu-Chen Lin - Doylestown PA, US
Li Liu - Germantown MD, US
John Mabus - East Greenville PA, US
Mark Macielag - Spring House PA, US
Mark McDonnell - Lansdale PA, US
Philip Pitis - North Wales PA, US
Yue-Mei Zhang - Spring House PA, US
Sui-Po Zhang - Malvern PA, US
Bin Zhu - Spring House PA, US
Assignee:
Janssen Pharmaceutica NV
International Classification:
A61K 31/496, C07D 295/108, C07D 409/12
US Classification:
51421018, 544359, 544379
Abstract:
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows:.
Tricyclic Delta Opioid Modulators
US Patent:
2010009, Apr 15, 2010
Filed:
Nov 20, 2009
Appl. No.:
12/622548
Inventors:
Steven J. Coats - Quaketown PA, US
Scott L. Dax - Landenberg PA, US
Bart DeCorte - Southhampton PA, US
Li Liu - Doylestown PA, US
Mark McDonnell - Lansdale PA, US
James J. McNally - Souderton PA, US
Scott L. Dax - Landenberg PA, US
Bart DeCorte - Southhampton PA, US
Li Liu - Doylestown PA, US
Mark McDonnell - Lansdale PA, US
James J. McNally - Souderton PA, US
International Classification:
A61K 31/5415, C07D 413/02, C07D 413/14, C07D 417/14, A61K 31/538
US Classification:
5142252, 544102, 544 46, 544 42, 5142298
Abstract:
The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic δ-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.