DR. MARK C POZNANSKY, MD PHD
Osteopathic Medicine at Fruit St, Boston, MA
License number
Massachusetts 157686
Category
Osteopathic Medicine
Type
Internal Medicine
License number
Massachusetts 157686
Category
Osteopathic Medicine
Type
Infectious Disease
Address
Address
55 Fruit St, Boston, MA 02114
Phone
(617) 726-3906
(617) 724-0287
(617) 726-2894 (Fax)
(617) 724-0287
(617) 726-2894 (Fax)
Personal information
See more information about MARK C POZNANSKY at radaris.comName
Address
Phone
64 Mandalay Rd, Newton Center, MA 02459
Charlestown, MA
16 Monument St, Charlestown, MA 02129
44 Irving St, Cambridge, MA 02138
64 Nauset Ave E, North Falmouth, MA 02556
Professional information
Purposeful Movement Of Human Migratory Cells Away From An Agent Source
US Patent:
6448054, Sep 10, 2002
Filed:
Apr 7, 2000
Appl. No.:
09/546153
Inventors:
Mark C. Poznansky - Charlestown MA
Andrew T. Luster - Wellesley MA
David T. Scadden - Weston MA
Andrew T. Luster - Wellesley MA
David T. Scadden - Weston MA
Assignee:
The General Hospital Corporation - Boston MA
International Classification:
C12N 999
US Classification:
4351841, 424 851
Abstract:
This invention relates to methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention relates to methods and compositions for modulating movement of cells of hematopoietic, neural, epithelial, or mesenchymal origin, in a specific site in a subject. The foregoing are useful, inter alia, in the treatment of conditions characterized by a need to modulate migratory-cell movement associated with specific sites in a subject. More specifically, specific sites include sites of inflammation and modulation of migratory-cell movement is movement away from an agent source, or repulsion. Other sites include tumor sites, sites of pathogenic infection, and germ cell bearing sites.
Director - Vaccine And Immunotherapy Center At Harvard Medical School
Position:
Director - Vaccine and Immunotherapy Center at Harvard Medical School
Location:
Greater Boston Area
Industry:
Higher Education
Work:
Harvard Medical School
-
Director - Vaccine and Immunotherapy Center
Purposeful Movement Of Human Migratory Cells Away From An Agent Source
US Patent:
2008030, Dec 4, 2008
Filed:
Nov 4, 2005
Appl. No.:
11/667410
Inventors:
Mark C. Poznansky - Charlestown MA, US
Fabrizio Vianello - Padova, IT
Natalia Papeta - Brookline MA, US
Fabrizio Vianello - Padova, IT
Natalia Papeta - Brookline MA, US
Assignee:
The General Hospital Corporation - Boston MA
International Classification:
A61K 38/19, A61K 31/395, A61K 31/192, C12Q 1/02, G01N 33/566, G01N 33/68, A61K 31/454
US Classification:
514 2, 514183, 514568, 514323, 436 86, 435 29, 436501
Abstract:
This invention provides methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention provides anti-fugetactic agents and methods for the use thereof in enhancing an immune response.
Lymphoid Tissue-Specific Cell Production From Hematopoietic Progenitor Cells In Three-Dimensional Devices
US Patent:
6548299, Apr 15, 2003
Filed:
May 18, 2000
Appl. No.:
09/574749
Inventors:
Mark J. Pykett - Newton MA 02165
Michael Rosenzweig - Boston MA 02116
David T. Scadden - Weston MA 02498
Mark C. Poznansky - Charlestown MA 02129
Michael Rosenzweig - Boston MA 02116
David T. Scadden - Weston MA 02498
Mark C. Poznansky - Charlestown MA 02129
International Classification:
C12N 506
US Classification:
435377, 435363, 435372, 4353723, 435373, 435395, 435402, 435352, 435 355, 623 16
Abstract:
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of lymphoreticular stromal cells and in the absence of exogenously added growth factors. The resulting differentiated progeny. The lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.
Compositions For Modulating Immune Cell Activity And Methods For Detection Thereof
US Patent:
2007000, Jan 11, 2007
Filed:
Jan 30, 2004
Appl. No.:
10/543850
Inventors:
Mark Poznansky - Charlestown MA, US
Diana Brainard - Boston MA, US
Diana Brainard - Boston MA, US
International Classification:
C12Q 1/70, C12Q 1/68, C12P 21/06
US Classification:
435069100, 435006000, 435005000
Abstract:
The invention relates to a new method for measuring cytotoxic activity of immune cells, and to methods and products for treating abnormal immune responses.
Lymphoid Tissue-Specific Cell Production From Hematopoietic Progenitor Cells In Three-Dimensional Devices
US Patent:
2008006, Mar 13, 2008
Filed:
Jan 31, 2007
Appl. No.:
11/701172
Inventors:
Mark Pykett - Boxford MA, US
Michael Rosenzweig - Boston MA, US
David Scadden - Weston MA, US
Mark Poznansky - Charlestown MA, US
Michael Rosenzweig - Boston MA, US
David Scadden - Weston MA, US
Mark Poznansky - Charlestown MA, US
Assignee:
Cytomatrix, LLC - Chelmsford MA
The General Hospital Corporation - Boston MA
The General Hospital Corporation - Boston MA
International Classification:
C12N 5/06
US Classification:
435373000
Abstract:
The invention relates to a method for lymphoid tissue-specific cell production from hematopoietic progenitor cells in unique, three-dimensional culture devices, in the presence of antigen presenting cells and lymphoreticular stromal cells, and in the absence of exogenously added growth factors. The resulting lymphoid tissue-specific cells may be isolated at any sequential stage of differentiation and further expanded. The lymphoid tissue-specific cells also may be genetically altered at any stage of the process.
Fugetactic Proteins, Compositions And Methods Of Use
US Patent:
7745578, Jun 29, 2010
Filed:
Jul 7, 2004
Appl. No.:
10/563726
Inventors:
Mark C. Poznansky - Charlestown MA, US
Dahlia Doughty - Charlestown MA, US
Dahlia Doughty - Charlestown MA, US
Assignee:
The General Hospital Corporation - Boston MA
International Classification:
C07K 7/00, C07K 14/00, A61K 38/00
US Classification:
530328, 530350, 514 12, 514 15
Abstract:
This invention relates to compositions and methods that modulate the movement of cells with migratory capacity. More specifically, the invention relates to compositions and methods for promoting migratory movement, fugetaxis, of cells from a specific site in a subject. The foregoing are useful, inter alia, in the treatment of conditions characterized by a need to promote migratory cell movement away from specific sites in a subject. Specific sites include sites of inflammation, infection, an autoimmune reaction, a tumor and a transplanted organ or tissue.
Immunotherapies Employing Self-Assembling Vaccines
US Patent:
2011012, Jun 2, 2011
Filed:
Apr 17, 2009
Appl. No.:
12/988445
Inventors:
Jeffrey A. Gelfand - Cambridge MA, US
Mark C. Poznansky - Charlestown MA, US
Pierre R. Leblanc - Stoneham MA, US
Svetlana E. Korochkina - Lexington MA, US
Mark C. Poznansky - Charlestown MA, US
Pierre R. Leblanc - Stoneham MA, US
Svetlana E. Korochkina - Lexington MA, US
International Classification:
A61K 39/395, A61K 38/02, A61K 35/00, A61K 35/76, A61K 35/74, A61K 36/06, A61K 35/68, A61K 39/00, A61K 39/12, A61K 39/02, A61P 37/04
US Classification:
4241781, 514 11, 424 931, 424 936, 424 937, 424 934, 424 935, 514 209, 4241931, 42419611, 42419711
Abstract:
Provided herein are self-assembling pharmaceutical compositions comprising a heat shock protein fused to a biotin-binding protein, wherein the biotin-binding protein is non-covalently bound to four biotinylated components, and further wherein at least two of the four biotinylated components are not identical.
Recovery Of Tissue Function Following Administration Of B Cells To Injured Tissue
US Patent:
7695712, Apr 13, 2010
Filed:
Apr 18, 2006
Appl. No.:
11/406508
Inventors:
Mark C. Poznansky - Charlestown MA, US
Traci T. Goodchild - Dunwoody GA, US
Mark T. Ungs - Minnetonka MN, US
Nicholas A. F. Chronos - Atlanta GA, US
Nadine Weich - Brookline MA, US
Traci T. Goodchild - Dunwoody GA, US
Mark T. Ungs - Minnetonka MN, US
Nicholas A. F. Chronos - Atlanta GA, US
Nadine Weich - Brookline MA, US
Assignee:
ACTX, Inc. - Atlanta GA
International Classification:
C12N 5/0781, A01N 65/00
US Classification:
424 937, 435372, 4353722
Abstract:
The present invention relates generally to systems and methods of enhancing recovery of function of injured tissue through administration of a composition comprising a relatively pure populations of B lymphocyte cells in a pharmaceutically acceptable carrier to the injured tissue. Kits are provided to aid in purification of B cells from heterogeneous mixtures of cells and administration of B cells to injured tissue.
Methods And Compositions Relating To Gradient Exposed Cells
US Patent:
2007013, Jun 14, 2007
Filed:
Dec 8, 2003
Appl. No.:
10/537610
Inventors:
Mark Poznansky - Charlestown MA, US
Rachel Rutishauer - New Haven CT, US
Rachel Rutishauer - New Haven CT, US
Assignee:
GENERAL HOSPITAL CORPORATION, THE - BOSTON MA
International Classification:
C12Q 1/68, C12N 15/09
US Classification:
435006000, 435455000
Abstract:
The invention relates to methods and compositions for stimulating or inhibiting directed cell migration.