Inventors:
Arjun G. Yodh - Merion PA, US
Joel H. Greenberg - Wayne PA, US
Guoqiang Yu - Flemington NJ, US
John A Detre - Wynnewood PA, US
Turgut Durduran - Upper Darby PA, US
Mark G. Burnett - Philadelphia PA, US
Harry Quon - Rose Valley PA, US
Stephen M. Hahn - Glen Mills PA, US
Assignee:
The Trustees Of The University Of Pennsylvania - Philadelphia PA
International Classification:
A61B 5/00, G01N 21/25
US Classification:
600310, 600323, 600328, 600344, 600407, 600473, 600474, 600475, 600476, 600477, 356406, 356477
Abstract:
An embodiment of the invention includes a device, system and method for determining the characteristics of deep tissue. The novel method includes measuring blood flow rate and oxygenation characteristics of the tissue, and determining oxygen metabolism of the tissue as a function of the measure blood flow rate and measure oxygenation. The blood flow rate characteristics are measured as a function of light fluctuations caused by the tissue, while the oxygenation characteristics are measured as a function of transmission of light through the tissue with respect to the wavelength of light. The tissue may be layered tissue, for example, a portion of a brain. The tissue characteristics may be measured during times of varying levels of exercise intensity.