DR. MARK B MECIKALSKI, MD
Osteopathic Medicine at Knight Dr, Tucson, AZ

5327883, Jul 12, 1994

May 20, 1991

7/702297

David R. Williams - San Diego CA
Mark B. Mecikalski - Tucson AZ
David O. Thueson - Poway CA

Dura Pharmaceuticals, Inc. - San Diego CA

A61M 1500

12820312

An apparatus for aerosolizing a dose of powdered medicine for inhalation, comprising in combination a solid core defining a diskshaped aerosolizing chamber, the chamber defined by spaced-apart, flat front and rear walls terminated by a circumferential wall, the core including a first end piece having formed therein a hollow mouth/nose piece at the front thereof, an impeller non-concentrically disposed in the chamber mounted on a shaft for high-speed powered rotation about a fixed axis, a plunger for instantaneously introducing a full dose of powdered medicine into the aerosolizing chamber so that all particles thereof are available for intermixing disaggregation and comminution, an aperture for receiving a first stream of air interior the core and passing it towards the mouthpiece for inhalation by the user, and, a wall having formed therein at least one aperture for diverting a portion of the first stream into a second stream of air for sweeping through the aerosolizing chamber to mix with the particles to form a fine, low-density, low-velocity, dry mist of powdered medicine for inhalation by the user.

5568807, Oct 29, 1996

Jul 13, 1995

8/501931

Mark B. Mecikalski - Tucson AZ

A61M 1500

12820321

An improved respiratory inhaler and medicated packet which uses a patient's breath to send powdered medication into the oral cavity of the patient. The respiratory inhaler is reusable and controls both the rate of airflow inside the chamber and prevents the patient from blowing into the respiratory inhaler. Disposable medicated packets are inserted into the respiratory inhaler. These medicated packets have preformed holes which pass air through the packet and entrain the medication. One respiratory inhaler can be used numerous times for numerous different types of medication. These medicated packets have a removable, protective layer to maintain the sterility and dryness of the measured dose of medication. In operation, the medication is transported from the packet, through the respiratory inhaler, and into the patient. The medicated packets are transparent on one side to allow the patient to observe if the medication has been completely delivered.

7802570, Sep 28, 2010

Dec 27, 2007

11/965662

Mark B. Mecikalski - Tucson AZ, US

Breathe Pharmaceuticals - San Diego CA

A61M 15/00, A61M 16/00

12820321, 12820312, 12820315, 12820319, 12820323, 12820324, 604 58, 222636

A drug transfer system is adapted to transfer a powdered drug into a patient via inhalation. The drug transfer system includes a drug container or packet that removably inserts into an inhaler device. As the patient inhales from the inhaler device, the drug flows from the container, through the inhaler device, and into the patient's respiratory system. The system is adapted for ease of use without requiring the user to perform any cumbersome manipulations of the drug packet during insertion into the inhaler or during inhalation of the drug.

5318016, Jun 7, 1994

Mar 30, 1993

8/039920

Mark B. Mecikalski - Tucson AZ

WE Pharmaceuticals, Inc. - Ramona CA

A61M 1100

12820023

A therapeutic inhalation device for receiving a dose of oronasal medication from a pressurized aerosol source and for delivering the same in dispersed and nonpressurized form to a breathing passage of a patient is comprised of top and bottom members and a collapsible sleeve attached at its opposite ends to the top and bottom members and defining therewith a spacer or breathing chamber that is extendable and contractible. The bottom member is cup-shaped and of a size to receive the sleeve and top member when the sleeve is collapsed and the top member is inserted into the bottom member, thereby to provide a device which, when not in use, is small and compact and conveniently stored and transported. The top member is provided with a guide member for positioning a medication containing aerosol canister for dispensing of its contents into the spacer chamber and an inhalation member communicating with the chamber for delivery of the medication to the patient in the form of a non-pressurized dilute dispersion. The guide and inhalation members are movable to retracted storage positions within the top member for convenience of storage and transportation.

6158428, Dec 12, 2000

Dec 21, 1998

9/217501

Mark Mecikalski - Tuscon AZ

We Pharmaceuticals Inc. - Romona CA

A61M 1100

12820023

An infant inhaler in which the aerosol medication is communicated into a flexible bag. Using a mask, during inhalation, the medicated air within the flexible bag is drawn into the infant's lungs; exhalation from the infant is exhausted into the atmosphere. By watching the deflation of the flexible bag, the care-giver is appraised of the progress of the medication's inhalation. The entire assembly is held with one hand allowing the infant to be cradled in the other arm. Refilling of the flexible bag with ambient air is accomplished by inverting the apparatus which causes the valves therein to open and allow ambient air into the flexible bag. Refilling the flexible bag with medication is done using a single hand by pressing the aerosol bottle against the apparatus.

6055980, May 2, 2000

Jul 22, 1998

9/120549

Mark B. Mecikalski - Tucson AZ
David R. Williams - San Diego CA
David O. Thueson - Poway CA

Dura Pharmaceuticals, Inc. - San Diego CA

A61M 1500

12820315

A dry powder medicine inhaler has an impeller non-concentrically disposed in a mixing chamber. A motor spins the impeller at high speed. A plunger introduces a dose of powdered medicine into the chamber so that all powder particles are available for intermixing disaggregation and comminution. An aperture receives a first stream of air and passes it towards the mouthpiece for inhalation by the user. A wall has at least one aperture for diverting a portion of a main air stream into the aerosolizing chamber to mix with the particles to form a fine, low-density, low velocity, dry mist of powdered medicine for inhalation by the user.

5575281, Nov 19, 1996

Jul 13, 1995

8/502331

Mark B. Mecikalski - Tucson AZ

A61M 1500

12820321

An improved inhaler and medicated packet which uses a patient's breath to send powdered medication into the oral cavity of the patient. The inhaler is reusable and controls both the rate of airflow inside the chamber and prevents the patient from blowing into the inhaler. Disposable medicated packets are inserted into the inhaler. These medicated packets have preformed holes which pass air through the packet and entrain the medication. One inhaler can be used numerous times for numerous different types of medication. These medicated packets have a removable, protective layer to maintain the sterility and dryness of the measured dose of medication. In operation, the medication is transported from the packet, through the inhaler, and into the patient. The medicated packets are transparent on one side to allow the patient to observe if the medication has been completely delivered.

5492112, Feb 20, 1996

Apr 14, 1994

8/227559

Mark B. Mecikalski - Tuscon AZ
David R. Williams - Temecula CA
David O. Thueson - Poway CA

Dura Pharmaceuticals, Inc. - San Diego CA

A61M 1500

12820315

A dry powder medicine inhaler has an impeller non-concentrically disposed in a mixing chamber. A motor spins the impeller at high speed. A plunger introduces a dose of powdered medicine into the chamber so that all powder particles are available for intermixing disaggregation and comminution. An aperture receives a first stream of air and passes it towards the mouthpiece for inhalation by the user. A wall has at least one aperture for diverting a portion of a main air stream into the aerosolizing chamber to mix with the particles to form a fine, low-density, low velocity, dry mist of powdered medicine for inhalation by the user.