MARIE COLETTE DEFRANCES
Medical Practice in Gibsonia, PA

License number
Pennsylvania MD070081L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Gibsonia, PA 15044

Personal information

See more information about MARIE COLETTE DEFRANCES at radaris.com
Name
Address
Phone
Marie Defrances
2115 Grove Dr, Gibsonia, PA 15044

Professional information

See more information about MARIE COLETTE DEFRANCES at trustoria.com
Marie Defrances Photo 1
Cell Death Modulation Via Antagonists Of Fasl And Fas Activation

Cell Death Modulation Via Antagonists Of Fasl And Fas Activation

US Patent:
2007018, Aug 9, 2007
Filed:
Apr 25, 2005
Appl. No.:
11/113951
Inventors:
Abdolreza Zarnegar - Gibsonia PA, US
Marie DeFrances - Gibsonia PA, US
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
C12P 21/06, C07K 7/06, C07K 7/08, C07K 14/715
US Classification:
435069100, 530350000, 435320100, 435325000, 530329000, 530330000
Abstract:
The invention provides a polypeptide that attenuates the activation of Fas, TNFR1, or both. The polypeptide can be used to treat conditions associated with dysregulation of the cell death or inflammatory pathway and can be formulated into pharmaceutical compositions for medical or veterinary use.


Marie Defrances Photo 2
Compounds And Methods For Inhibiting Apoptosis

Compounds And Methods For Inhibiting Apoptosis

US Patent:
2008028, Nov 13, 2008
Filed:
Dec 1, 2006
Appl. No.:
11/607396
Inventors:
Reza Zarnegar - Gibsonia PA, US
Marie C. DeFrances - Gibsonia PA, US
Trina L. Foster - Ottawa, CA
George L. McLendon - Durham NC, US
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
Duke University - Durham NC
International Classification:
A61K 38/07, C07K 5/00, C07K 7/06, A61K 38/08, A61P 35/00
US Classification:
514 16, 530330, 514 18, 530328
Abstract:
The invention provides compounds, compositions, and methods for inhibiting apoptosis and for the treatment of conditions related thereto.