MARIE COLETTE DEFRANCES
Medical Practice in Gibsonia, PA
License number
Pennsylvania MD070081L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Gibsonia, PA 15044
Personal information
See more information about MARIE COLETTE DEFRANCES at radaris.comName
Address
Phone
2115 Grove Dr, Gibsonia, PA 15044
Professional information
Cell Death Modulation Via Antagonists Of Fasl And Fas Activation
US Patent:
2007018, Aug 9, 2007
Filed:
Apr 25, 2005
Appl. No.:
11/113951
Inventors:
Abdolreza Zarnegar - Gibsonia PA, US
Marie DeFrances - Gibsonia PA, US
Marie DeFrances - Gibsonia PA, US
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
International Classification:
C12P 21/06, C07K 7/06, C07K 7/08, C07K 14/715
US Classification:
435069100, 530350000, 435320100, 435325000, 530329000, 530330000
Abstract:
The invention provides a polypeptide that attenuates the activation of Fas, TNFR1, or both. The polypeptide can be used to treat conditions associated with dysregulation of the cell death or inflammatory pathway and can be formulated into pharmaceutical compositions for medical or veterinary use.
Compounds And Methods For Inhibiting Apoptosis
US Patent:
2008028, Nov 13, 2008
Filed:
Dec 1, 2006
Appl. No.:
11/607396
Inventors:
Reza Zarnegar - Gibsonia PA, US
Marie C. DeFrances - Gibsonia PA, US
Trina L. Foster - Ottawa, CA
George L. McLendon - Durham NC, US
Marie C. DeFrances - Gibsonia PA, US
Trina L. Foster - Ottawa, CA
George L. McLendon - Durham NC, US
Assignee:
University of Pittsburgh of the Commonwealth System of Higher Education - Pittsburgh PA
Duke University - Durham NC
Duke University - Durham NC
International Classification:
A61K 38/07, C07K 5/00, C07K 7/06, A61K 38/08, A61P 35/00
US Classification:
514 16, 530330, 514 18, 530328
Abstract:
The invention provides compounds, compositions, and methods for inhibiting apoptosis and for the treatment of conditions related thereto.