Inventors:
Michael R. ROBINSON - Irvine CA, US
James A. Burke - Santa Ana CA, US
Hui Liu - Irvine CA, US
Werhner C. Orilla - Anaheim CA, US
Lon T. Spada - Walnut CA, US
Scott Whitcup - Laguna Hills CA, US
Patrick M. Hughes - Aliso Viejo CA, US
Kun Xu - Laguna Niguel CA, US
Marianne M. Do - Orange CA, US
Assignee:
ALLERGAN, INC. - Irvine CA
International Classification:
A61F 2/00, A61K 31/215, A61K 31/165, A61K 9/14, A61K 31/4025, A61K 31/426, A61K 31/415, A61K 31/42
US Classification:
424426, 514530, 514622, 424501, 514422, 514369, 514385, 514376
Abstract:
Biocompatible, bioerodible sustained release implants and microspheres for intracameral or anterior vitreal placement include an anti-hypertensive agent and a biodegradable polymer effective to treat an ocular hypertensive condition (such as glaucoma) by relapsing therapeutic amount of the anti-hypertensive agent over a period of time between days and year.