Inventors:
Katherine A. High - Merion PA, US
Marcela V. Maus - New York NY, US
Federico Mingozzi - Philadelphia PA, US
Daniel J. Hui - Chesterbrook PA, US
Assignee:
THE CHILDREN'S HOSPITAL OF PHILADELPHIA - PHILADELPHIA PA
International Classification:
A61K 48/00, C07K 14/715, C12Q 1/70, A61K 38/17, C12N 15/63, A61P 37/00
US Classification:
514 12, 530350, 435 5, 514 44 R, 4353201
Abstract:
Compositions and methods are provided for inhibiting T cell mediated destruction of virally transduced, trangene containing cells.