DR. MARC S COHEN, MD
Urology at Archer Rd, Gainesville, FL
License number
Florida ME58081
Category
Radiology
Type
Urology
Address
Address
2
1600 SW Archer Rd, Gainesville, FL 32610
PO Box 918025, Orlando, FL 32891
PO Box 918025, Orlando, FL 32891
Phone
(352) 273-6815
(352) 392-8846 (Fax)
(352) 392-8846 (Fax)
Professional information
Marc S Cohen, Gainesville FL
Specialties:
Urologist
Address:
1600 Sw Archer Rd, Gainesville, FL 32610
Education:
University of Miami, Miller School of Medicine - Doctor of Medicine
University of Texas Medical Branch Galveston, The - Residency - Urological Surgery
Boston Medical Center - Internship - Surgery
University of Texas Medical Branch Galveston, The - Residency - Urological Surgery
Boston Medical Center - Internship - Surgery
Board certifications:
American Board of Urology Certification in Urology
Marc Singman Cohen, Gainesville FL
Specialties:
Urology, Surgery
Work:
Urology At Shands Medical
2000 SW Archer Rd, Gainesville, FL 32608 Shands at AGH
1600 Sw Archer Rd, Gainesville, FL 32610
2000 SW Archer Rd, Gainesville, FL 32608 Shands at AGH
1600 Sw Archer Rd, Gainesville, FL 32610
Education:
University of Miami(1975) Urology
Compositions And Devices For Controlled Release Of Active Ingredients
US Patent:
5607417, Mar 4, 1997
Filed:
Feb 1, 1995
Appl. No.:
8/382315
Inventors:
Christopher D. Batich - Gainesville FL
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
Assignee:
CApHCO, Inc. - Gainesville FL
International Classification:
A61K 922
US Classification:
6048901
Abstract:
A method for the controlled release of a biologically active agent wherein the agent is released from a hydrophobic, pH-sensitive polymer matrix is disclosed and claimed. The polymer matrix swells when the environment reaches pH 8. 5, releasing the active agent. A polymer of hydrophobic and weakly acidic comonomers is disclosed for use in the controlled release system. Further disclosed is a specific embodiment in which the controlled release system may be used. The pH-sensitive polymer is coated onto a latex catheter used in ureteral catheterization. A common problem with catheterized patients is the infection of the urinary tract with ureaseproducing bacteria. In addition to the irritation caused by the presence of the bacteria, urease produced by these bacteria degrade urea in the urine, forming carbon dioxide and ammonia. The ammonia causes an increase in the pH of the urine. Minerals in the urine begin to precipitate at this high pH, forming encrustations which complicate the functioning of the catheter.
Compositions And Devices For Controlled Release Of Active Ingredients
US Patent:
5554147, Sep 10, 1996
Filed:
Feb 1, 1994
Appl. No.:
8/189854
Inventors:
Christopher D. Batich - Gainesville FL
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
Assignee:
CApHCO, Inc. - Gainesville FL
International Classification:
A61K 922
US Classification:
6048901
Abstract:
A method for the controlled release of a biologically active agent wherein the agent is released from a hydrophobic, pH-sensitive polymer matrix is disclosed and claimed. The polymer matrix swells when the environment reaches pH 8. 5, releasing the active agent. A polymer of hydrophobic and weakly acidic comonomers is disclosed for use in the controlled release system. Further disclosed is a specific embodiment in which the controlled release system may be used. The pH-sensitive polymer is coated onto a latex catheter used in ureteral catheterization. A common problem with catheterized patients is the infection of the urinary tract with urease-producing bacteria. In addition to the irritation caused by the presence of the bacteria, urease produced by these bacteria degrade urea in the urine, forming carbon dioxide and ammonia. The ammonia causes an increase in the pH of the urine. Minerals in the urine begin to precipitate at this high pH, forming encrustations which complicate the functioning of the catheter.
Compositions And Devices For Controlled Release Of Active Ingredients
US Patent:
5788687, Aug 4, 1998
Filed:
Jul 31, 1995
Appl. No.:
8/509120
Inventors:
Christopher D. Batich - Gainesville FL
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
William Toreki - Gainesville FL
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
William Toreki - Gainesville FL
Assignee:
CApHCO, Inc - Gainesville FL
International Classification:
A61K 922
US Classification:
6048901
Abstract:
A method for the controlled release of a biologically active agent wherein the agent is released from a hydrophobic, pH-sensitive polymer matrix is disclosed and claimed. In one embodiment, the polymer matrix swells when the environment reaches pH 8. 5, releasing the active agent. A polymer of hydrophobic and weakly acidic comonomers is disclosed for use in the controlled release system. In another embodiment, weakly basic comonomers are used and the active agent is released as the pH drops. Further disclosed is a specific embodiment in which the controlled release system may be used. The pH-sensitive polymer is coated onto a latex catheter used in ureteral catheterization. A common problem with catheterized patients is the infection of the urinary tract with urease-producing bacteria. In addition to the irritation caused by the presence of the bacteria, urease produced by these bacteria degrade urea in the urine, forming carbon dioxide and ammonia. The ammonia causes an increase in the pH of the urine.
Compositions And Devices For Controlled Release Of Active Ingredients
US Patent:
6306422, Oct 23, 2001
Filed:
Aug 3, 1998
Appl. No.:
9/128252
Inventors:
Christopher D. Batich - Gainesville FL
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
William Toreki - Gainesville FL
Marc S. Cohen - Gainesville FL
Kirk Foster - Baltimore MD
William Toreki - Gainesville FL
Assignee:
CApHCO, Inc. - Jacksonville FL
International Classification:
A61M 2700, A61K 4732
US Classification:
424423
Abstract:
A method for the controlled release of a biologically active agent wherein the agent is released from a hydrophobic, pH-sensitive polymer matrix is disclosed and claimed. In one embodiment, the polymer matrix swells when the environment reaches pH 8. 5, releasing the active agent. A polymer of hydrophobic and weakly acidic comonomers is disclosed for use in the controlled release system. In another embodiment, weakly basic comonomers are used and the active agent is released as the pH drops. Further disclosed is a specific embodiment in which the controlled release system may be used. The pH-sensitive polymer is coated onto a latex catheter used in ureteral catheterization. A common problem with catheterized patients is the infection of the urinary tract with urease-producing bacteria. In addition to the irritation caused by the presence of the bacteria, urease produced by these bacteria degrade urea in the urine, forming carbon dioxide and ammonia. The ammonia causes an increase in the pH of the urine.