Inventors:
Yiyun Huang - Scarsdale NY, US
Marc Laruelle - Scarsdale NY, US
International Classification:
A61K 49/10, C07C 211/49, A61P 43/00
Abstract:
This invention provides a compound having the structure:This invention also provides for related compounds and pharmaceutical compositions. This invention further provides for a compound that can be used for non-invasive method for positron emission tomography (PET) imaging of serotonin transporter sites in mammals comprising labeling serotonin transporter sites (SERT) with an image-generating amount of the radiolabeled compound disclosed herein and measuring spatial distribution of the compound in the mammal by PET so as to thereby image the serotonin transporter sites.