Inventors:
Jagdish Parasrampuria - Bridgewater NJ, US
Maxine B. Yonker - Emerald Hills CA, US
Kenneth E. Schwartz - San Mateo CA, US
Marc J. Gurwith - Los Altos CA, US
Assignee:
Genelabs Technologies, Inc. - Redwood City CA
International Classification:
A61K 31/56
US Classification:
514170, 514169, 514177, 514178, 514180
Abstract:
Disclosed are improved pharmaceutical formulations comprising dehydroepiandrosterone (DHEA), enriched in selected polymorphic forms, for therapeutic applications. In one embodiment, the formulation comprises, in solid form, DHEA, at least 85% of which is present as a single polymorph selected from the form I polymorph or the form II polymorph, and at least one pharmaceutical excipient. Methods for making and using such compositions are also disclosed.