Inventors:
Marc E. Lippman - Coral Gables FL, US
Harry James Hnatyszyn - Coral Gables FL, US
Mingli Liu - Marietta GA, US
James M. Rae - Dexter MI, US
Assignee:
UNIVERSITY OF MIAMI - Miami FL
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61K 51/00, A61K 39/395, A61K 39/00, C07K 14/00, A61P 35/00, C07K 16/18, C07H 21/04
US Classification:
424 149, 4241741, 4241781, 530350, 5303879, 5303881, 5303891, 5303913, 536 231
Abstract:
The generation and validation of a novel monoclonal GREB1 antibody (GREB1ab). Methods for the prognosis, diagnosis, assessment of disease progression, severity and outcome utilize GREB1 molecules as biomarkers. The GREB1 antibody is also a useful tool for investigations focused on the expression, distribution and function of GREB1 in normal and cancer tissues.