Inventors:
Rosalyn D. Blumenthal - Belleville NJ
Walter Lew - Caldwell NJ
Malik Juweid - Bloomfield NJ
Rita Alisauskas - Hopatcong NJ
Zhiliang Ying - East Brunswick NJ
David M. Goldenberg - Mendham NJ
Assignee:
Center for Molecular Medicine and Immunology - Belleville NJ
International Classification:
G01N 3353
US Classification:
435 71, 435 72, 435 721, 530351, 5303879, 53038823
Abstract:
The invention provides kits and methods for evaluating the myelosuppressive state of a patient. These methods and kits provide a useful adjunct for cytotoxic and myelosuppressive therapies. By establishing threshold levels of certain cytokines as a surrogate for myelosuppression, treatment protocols can be optimized to reduce myelotoxicity, while maximizing effective dose.