Inventors:
Maida Wong - Los Angeles CA, US
Brian Skaggs - Encino CA, US
Elaine Lourenco - Los Angeles CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 31/4704
Abstract:
Provided herein are compositions and methods associated with the prevention and treatment of lupus nephritis. In particular, provided herein is a method for delaying onset of active lupus nephritis in a subject at risk for developing active lupus nephritis, comprising periodically administering to the subject an amount of laquinimod effective to delay onset of active lupus nephritis in the subject. Also provided herein are laquinimod (LAQ) and a pharmaceutical composition comprising an amount of LAQ for use in delaying onset of active lupus nephritis in a subject at risk for developing active lupus nephritis.