Luisa Mestroni
Physician at Rockmont Cir, Boulder, CO
License number
Colorado 37486
Issued Date
Mar 25, 1999
Renew Date
May 1, 2015
Expiration Date
Apr 30, 2017
Type
Physician
Address
Address
1443 Rockmont Cir, Boulder, CO 80305
Professional information
Endothelin Single Nucleotide Polymorphisms And Methods Of Predicting B-Adrenergic Receptor Targeting Agent Efficacy
US Patent:
2010029, Nov 25, 2010
Filed:
Jul 28, 2008
Appl. No.:
12/670966
Inventors:
Matthew R. G. Taylor - Denver CO, US
Luisa Mestroni - Boulder CO, US
Luisa Mestroni - Boulder CO, US
International Classification:
A61K 31/403, C12Q 1/68, G01N 33/50, A61K 31/4035, A61K 31/167, A61K 31/138, A61K 31/164, A61P 9/04, A61P 9/00
US Classification:
514411, 435 6, 436 94, 514415, 514616, 514651, 514620
Abstract:
The present invention concerns the use of methods for evaluating β-adrenergic receptor targeting agent treatment for a patient, particularly one with a heart condition. In general, the disclosed methods entail determining the presence or absence of one or more polymorphisms in an endothelin gene system member. Based on the results of this determination, a β-adrenergic receptor targeting agent may be prescribed, administered or a treatment regimen altered, including the administration of a β-blocker. Accordingly, methods of treatment are also described.