DR. LOREN DAVID WALENSKY, MD PHD
Medical Practice in Boston, MA
License number
Massachusetts 204839
Category
Medical Practice
Type
Pediatric Hematology-Oncology
Address
Address
44 Jimmy Fund Clinic, Boston, MA 02115
Phone
(617) 632-6794
(617) 632-3310 (Fax)
(617) 632-6307
(617) 632-6401 (Fax)
(617) 632-3310 (Fax)
(617) 632-6307
(617) 632-6401 (Fax)
Personal information
See more information about LOREN DAVID WALENSKY at radaris.comName
Address
Phone
811 Commonwealth Ave, Newton Center, MA 02459
9 Goodnough Rd, Chestnut Hill, MA 02467
9 Goodnough, Brookline, MA 02467
9 Park Vale, Brookline, MA 02446
Professional information
See more information about LOREN DAVID WALENSKY at trustoria.com
Loren David Walensky, Boston MA
Loren David Walensky, Boston MA
Specialties:
Pediatrics, Pediatric Hematology-Oncology, Hematology & Oncology
Work:
Dana-Farber Cancer Institute
44 Binney St, Boston, MA 02115 Dana-Farber Cancer Institute
450 Brookline Ave, Boston, MA 02215 Children's Hospital
300 Longwood Ave, Boston, MA 02115
44 Binney St, Boston, MA 02115 Dana-Farber Cancer Institute
450 Brookline Ave, Boston, MA 02215 Children's Hospital
300 Longwood Ave, Boston, MA 02115
Education:
Johns Hopkins University (1997)
Dr. Loren D Walensky, Framingham MA - MD (Doctor of Medicine)
Dr. Loren D Walensky, Framingham MA - MD (Doctor of Medicine)
Specialties:
Pediatric Hematology & Oncology
Address:
761 Worcester Rd, Framingham 01701
(508) 788-1700 (Phone)
(508) 788-1700 (Phone)
Certifications:
Pediatric Oncology & Pediatric Hematology, 2012, Pediatrics, 2010
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
761 Worcester Rd, Framingham 01701
Brigham and Women's Hospital
75 Francis St, Boston 02115
Massachusetts General Hospital
55 Fruit St, Boston 02114
North Shore Medical Center - Salem Hospital
81 Highland Ave, Salem 01970
Brigham and Women's Hospital
75 Francis St, Boston 02115
Massachusetts General Hospital
55 Fruit St, Boston 02114
North Shore Medical Center - Salem Hospital
81 Highland Ave, Salem 01970
Education:
Medical School
Johns Hopkins University School Of Medicine
Graduated: 1997
Children's Hospital
Johns Hopkins University School Of Medicine
Graduated: 1997
Children's Hospital
Stabilized Alpha Helical Peptides And Uses Thereof
Stabilized Alpha Helical Peptides And Uses Thereof
US Patent:
7723469, May 25, 2010
Filed:
Nov 5, 2004
Appl. No.:
10/981873
Inventors:
Loren D. Walensky - Chestnut Hill MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer, legal representative - Weston MA, US
Gregory Verdine - Newton MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer, legal representative - Weston MA, US
Gregory Verdine - Newton MA, US
Assignee:
Dana-Farber Cancer Institute, Inc. - Boston MA
International Classification:
C07K 7/50
US Classification:
530317, 530326, 514 9
Abstract:
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
Methods Of Modulating Cellular Homeostatic Pathways And Cellular Survival
Methods Of Modulating Cellular Homeostatic Pathways And Cellular Survival
US Patent:
2010027, Oct 28, 2010
Filed:
May 2, 2008
Appl. No.:
12/598479
Inventors:
Stanley J. Korsmeyer - Weston MA, US
Susan R. Korsmeyer - Weston MA, US
Nika N. Danial - Boston MA, US
Loren D. Walensky - Chestnut Hill MA, US
Gregory Bird - Pelham NH, US
Susan R. Korsmeyer - Weston MA, US
Nika N. Danial - Boston MA, US
Loren D. Walensky - Chestnut Hill MA, US
Gregory Bird - Pelham NH, US
International Classification:
A61K 38/02, C12N 5/0781, C07K 14/00, C07K 7/08, A61P 3/10, A61P 3/04
US Classification:
514 73, 514 69, 435375, 514 11, 530324, 530325, 530326
Abstract:
The invention provides composition and therapeutic, methods for modulating homeostatic pathways that are useful in treatment, and prevention of diabetes, diabetes associated disorders, metabolic disorders and cancer.
Methods And Compositions For Modulating Bcl-2 Family Polypeptides
Methods And Compositions For Modulating Bcl-2 Family Polypeptides
US Patent:
2010028, Nov 11, 2010
Filed:
Sep 26, 2008
Appl. No.:
12/680098
Inventors:
Loren D. Walensky - Chestnut Hill MA, US
Nico Tjandra - Rockville MD, US
Evripidis Gavathiotis - Quincy MA, US
Motoshi Suzuki - Rockville MD, US
Gregory H. Bird - Pelham NH, US
Nico Tjandra - Rockville MD, US
Evripidis Gavathiotis - Quincy MA, US
Motoshi Suzuki - Rockville MD, US
Gregory H. Bird - Pelham NH, US
Assignee:
DANA FARBER CANCER INSTITUTE - Boston MA
NATIONAL INSTITUTES OF HEALTH - Rockville MD
NATIONAL INSTITUTES OF HEALTH - Rockville MD
International Classification:
A61P 43/00, G01N 33/53, A61K 38/16, C07K 14/435
US Classification:
514 189, 435 71, 514 214, 530326, 530350
Abstract:
The present invention is based, at least in part, on the identification of a novel active site on BCL-2 family polypeptide such as BAX, which when bound by a compound, modifies the activity of the BCL-2 family polypeptide.
Stabilized Alpha Helical Peptides And Uses Thereof
Stabilized Alpha Helical Peptides And Uses Thereof
US Patent:
2012008, Apr 5, 2012
Filed:
Oct 4, 2011
Appl. No.:
13/252751
Inventors:
Loren D. Walensky - Chestnut Hill MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer - Weston MA, US
Gregory Verdine - Newton MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer - Weston MA, US
Gregory Verdine - Newton MA, US
International Classification:
A61K 31/787, A61P 35/02, A61P 11/06, A61P 29/00, A61P 19/02, A61P 1/00, A61P 25/00, A61P 3/10, A61P 9/10, A61P 9/00, A61P 9/04, A61P 9/12, A61P 13/12, A61P 3/06, A61P 35/00
US Classification:
424 7817
Abstract:
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
Stabilized Alpha Helical Peptides And Uses Thereof
Stabilized Alpha Helical Peptides And Uses Thereof
US Patent:
8198405, Jun 12, 2012
Filed:
Jul 30, 2008
Appl. No.:
12/182673
Inventors:
Loren D. Walensky - Chestnut Hill MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer, legal representative - Weston MA, US
Gregory Verdine - Newton MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer, legal representative - Weston MA, US
Gregory Verdine - Newton MA, US
Assignee:
Dana-Farber Cancer Institute, Inc. - Boston MA
President and Fellows of Harvard College - Cambridge MA
President and Fellows of Harvard College - Cambridge MA
International Classification:
C07K 14/00
US Classification:
530324, 530323, 530317, 514 11, 514 189
Abstract:
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
Compositions And Methods For The Treatment Of Viral Infections
Compositions And Methods For The Treatment Of Viral Infections
US Patent:
2011031, Dec 29, 2011
Filed:
Jul 23, 2010
Appl. No.:
12/864375
Inventors:
Loren D. Walensky - Chestnut Hill MA, US
Assignee:
DANA FARBER CANCER INSTITUTE, INC. - Boston MA
International Classification:
A61K 39/395, C07K 14/155, C07K 14/135, C07K 14/115, C07K 14/11, C07K 14/165, C07K 14/08, A61K 38/10, A61K 38/16, C12N 7/06, C07K 16/10, A61P 31/18, A61P 31/16, A61P 31/14, C07K 7/08
US Classification:
4241391, 530326, 530324, 514 38, 514 37, 435238, 5303879
Abstract:
The invention provides compositions, kits and methods utilizing polypeptides having a viral alpha-helix heptad repeat domain in a stabilized a-helical structure (herein also referred to as SAH). The compositions are useful for treating and/or preventing viral infections. The invention is based, at least in part, on the result provided herein demonstrating that viral hydrocarbon stapled alpha helical peptides display excellent proteolytic, acid, and thermal stability, restore the native alpha-helical structure of the peptide, are highly effective in interfering with the viral fusogenic process, and possess superior pharmacokinetic properties compared to the corresponding unmodified peptides.
Stabilized Alpha Helical Peptides And Uses Thereof
Stabilized Alpha Helical Peptides And Uses Thereof
US Patent:
2009014, Jun 11, 2009
Filed:
Sep 18, 2008
Appl. No.:
12/233555
Inventors:
Loren D. Walensky - Chestnut Hill MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer - Weston MA, US
Gregory Verdine - Newton MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer - Weston MA, US
Gregory Verdine - Newton MA, US
International Classification:
C07K 1/00, C07K 14/00
US Classification:
530324, 530326, 530345
Abstract:
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
Stabilized P53 Peptides And Uses Thereof
Stabilized P53 Peptides And Uses Thereof
US Patent:
2010016, Jul 1, 2010
Filed:
Jan 31, 2008
Appl. No.:
12/525123
Inventors:
Federico Bernal - Brookline MA, US
Loren D. Walensky - Chestnut Hill MA, US
Gregory L. Verdine - Newton MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer - Weston MA, US
Loren D. Walensky - Chestnut Hill MA, US
Gregory L. Verdine - Newton MA, US
Stanley J. Korsmeyer - Weston MA, US
Susan Korsmeyer - Weston MA, US
International Classification:
C07K 14/435
US Classification:
530350
Abstract:
Cross-linked peptides related to human p53 and bind to HMD2 or a family member of HDM2 useful for promoting apoptosis, e.g., in the treatment of and identifying therapeutic agents that binding to HMD2 or a family member of HDM2.
Medical Practice licenses in Massachusetts
Other Doctors licenses in Massachusetts
GREATER BOSTON CHINESE GOLDEN AGE CENTER, INC., Agencies, 75 Kneeland St SUITE 204, Boston, MA 02111