Inventors:
Manuel Penichet - Los Angeles CA, US
Jay Dela Cruz - Inglewood CA, US
Lisan Peng - Tuscon AZ, US
Sherie Morrison - Los Angeles CA, US
Assignee:
The Regents of the University of California
International Classification:
A61K039/395, C07K016/46, C07K014/52
US Classification:
530/351000, 530/391100, 424/085100, 424/178100
Abstract:
The present invention provides methods of use of various antibody-immunostimulant fusion proteins as adjuvants of antigenic protein vaccinations to elicit humoral and/or cellular immune responses in vaccinated subjects. Compositions which include these fusion proteins and innate and/or exogenous antigenic proteins are also provided.