Inventors:
Jon Astle - Taunton MA, US
Christopher Burgess - Westwood MA, US
Theodore Catino - Attleboro MA, US
Poornima Dwivedi - Alamo CA, US
Maryanne Huntress - Attleboro MA, US
Karen Johnson - Acton MA, US
Marcia Lewis - Cohasset MA, US
Peter Maimonis - Westwood MA, US
Gary Molino - Norfolk MA, US
Susan Myerow - Lexington MA, US
Arunthathi Thiagalingam - Lexington MA, US
Lisa Boardman - Rochester MN, US
Lawrence Burgart - Rochester MN, US
Stephen Thibodeau - Rochester MN, US
International Classification:
G01N033/567, G01N033/574
Abstract:
The present invention relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1 or TIMP1 nucleic acid or amino acid molecules in a clinical sample obtained from the patient, wherein Reg1 or TIMP1 expression is indicative of the presence of colorectal cancer. The invention further relates to a method for detecting the presence of colorectal cancer in an individual, wherein colorectal cancer is detected by detecting the presence of Reg1 or TIMP1 nucleic acid or amino acid molecules in a clinical sample, in addition to detecting the presence of one or more additional colorectal cancer associated markers.