Inventors:
Yuqiang Wang - Guangzhou, CN
Jie Jiang - Guangzhou, CN
Pei Yu - Guangzhou, CN
Yewei Sun - Guangzhou, CN
Linda Wang - Cupertino CA, US
Zaijun Zhang - Guangzhou, CN
International Classification:
A61K 31/505, C07D 239/30, A61P 25/00, A61P 9/00, A61P 27/02, A61P 29/00, A61P 35/00
Abstract:
The present invention provides novel nitrones, their preparation and use. The novel compounds have the following formula: I The compounds of the present invention have strong antioxidative activity, and are thrombolytic. These compounds can be used to treat and/or prevent diseases caused by overproduction of free radicals and/or formation of thrombus.