LINDA HELEN LEE
Dentist in San Mateo, CA
License number
Pennsylvania DS035338
Category
Dentistry
Type
Dentist
Address
Address
2
San Mateo, CA 94404
Pennsylvania
Pennsylvania
Professional information
Linda Lee
Position:
HR Consultant at AtHoc, Auriq Systems and Asian Tapas
Location:
San Mateo, California
Industry:
Human Resources
Work:
AtHoc, Auriq Systems and Asian Tapas
- San Mateo and Los Angelese, CA since Jul 2008
-
HR Consultant
Education:
University of California, Los Angeles 1987 - 1991
BA, Anthropology Webster Jr. High
BA, Anthropology Webster Jr. High
Languages:
Chinese
Dr. Linda H Lee, Foster City CA - DMD (Doctor of Dental Medicine)
Specialties:
Oral & Maxillofacial Surgery
Address:
1261 E Hillsdale Blvd STE 1, Foster City 94404
(650) 525-1033 (Phone), (650) 525-1833 (Fax)
(650) 525-1033 (Phone), (650) 525-1833 (Fax)
Languages:
English
Education:
Medical School
UNIVERSITY OF CALIFORNIA AT SAN FRANCISCO
UNIVERSITY OF CALIFORNIA AT SAN FRANCISCO
Linda Helen Lee, Foster City CA
Specialties:
Oral Surgeon
Address:
1261 E Hillsdale Blvd, Foster City, CA 94404
4,7-Dichlororhodamine Dyes
US Patent:
2009009, Apr 9, 2009
Filed:
Aug 27, 2008
Appl. No.:
12/199441
Inventors:
Linda G. Lee - Foster City CA, US
Scott C. Benson - Foster City CA, US
Barnett B. Rosenblum - Foster City CA, US
Sandra L. Spurgeon - Foster City CA, US
Ronald J. Graham - Foster City CA, US
Scott C. Benson - Foster City CA, US
Barnett B. Rosenblum - Foster City CA, US
Sandra L. Spurgeon - Foster City CA, US
Ronald J. Graham - Foster City CA, US
Assignee:
Applied Biosystems Inc. - Foster City CA
International Classification:
C07H 21/00, C07H 19/10
US Classification:
536 243, 536 262
Abstract:
A set of 4,7-dichlororhodamine compounds useful as fluorescent dyes are disclosed having the structureswherein R-Rare hydrogen, fluorine, chlorine, lower alkyl, lower alkene, lower alkyne, sulfonate, sulfone, amino, amido, nitrile, lower alkoxy, linking group, or, when taken together, Rand Ris benzo, or, when taken together, Rand Ris benzo; R-R, R-Rand Rmay be hydrogen, fluorine, chlorine, lower alkyl lower alkene, lower alkyne, sulfonate, sulfone, amino, amido, nitrile, lower alkoxy, linking group; Rand Rmay be hydrogen, lower alkyl lower alkene, lower alkyne, phenyl, aryl, linking group; Y-Yare hydrogen, lower alkyl or cycloalkyl, or, when taken together, Yand R, Yand RYand R, and/or Yand Ris propano, ethano, or substituted forms thereof, and X-Xtaken separately are hydrogen, chlorine, fluorine, lower alkyl, carboxylate, sulfonate, hydroxymethyl, and linking group, or any combinations thereof. In another aspect, the invention includes reagents labeled with the 4,7-dichlororhodamine dye compounds, including deoxynucleotides, dideoxynucleotides, and polynucleotides. In an additional aspect, the invention includes methods utilizing such dye compounds and reagents including dideoxy polynucleotide sequencing and fragment analysis methods.
Water-Soluble Rhodamine Dye Conjugates
US Patent:
7504496, Mar 17, 2009
Filed:
Feb 14, 2005
Appl. No.:
11/059035
Inventors:
Linda G. Lee - Foster City CA, US
Ronald J. Graham - Foster City CA, US
William E. Werner - Foster City CA, US
Elana Swartzman - Foster City CA, US
Lily Lu - Foster City CA, US
Ronald J. Graham - Foster City CA, US
William E. Werner - Foster City CA, US
Elana Swartzman - Foster City CA, US
Lily Lu - Foster City CA, US
International Classification:
C07G 3/00, C07H 21/02, C07H 21/00, C07H 21/04, C07H 19/04, C12Q 1/68
US Classification:
536 266, 536 41, 536 231, 536 243, 536 253, 435 6
Abstract:
The present invention provides novel, water-soluble, red-emitting fluorescent rhodamine dyes and red-emitting fluorescent energy-transfer dye pairs, as well as labeled conjugates comprising the same and methods for their use. The dyes, energy-transfer dye pairs and labeled conjugates are useful in a variety of aqueous-based applications, particularly in assays involving staining of cells, protein binding, and/or analysis of nucleic acids, such as hybridization assays and nucleic acid sequencing.