LIN ZHANG
Pharmacy in Nutley, NJ
License number
New Jersey 28RH00032700
Issued Date
Apr 18, 2013
Expiration Date
Apr 18, 2015
Category
Pharmacy
Type
Pharmacist Intern
Address
Address
Nutley, NJ
Professional information
Pharmaceutical Solid Dosage Forms Comprising Amorphous Compounds Micro-Embedded In Ionic Water-Insoluble Polymers
US Patent:
2008010, May 8, 2008
Filed:
Oct 2, 2007
Appl. No.:
11/866102
Inventors:
Antonio Albano - Clifton NJ, US
Wantanee Phuapradit - Montville NJ, US
Navnit Shah - Clifton NJ, US
Zhongshui Yu - Bridgewater NJ, US
Lin Zhang - Nutley NJ, US
Wantanee Phuapradit - Montville NJ, US
Navnit Shah - Clifton NJ, US
Zhongshui Yu - Bridgewater NJ, US
Lin Zhang - Nutley NJ, US
International Classification:
A61K 9/48, A61K 31/4965
US Classification:
424451000, 514255060
Abstract:
The present invention provides novel pharmaceutical solid dosage forms for oral administration comprising a therapeutically effective amount of an unstable crystalline form or an amorphous form of a therapeutically effective compound micro-embedded into an ionic water-insoluble polymer. The therapeutically effective compounds, which have a tendency to gel, are micro-embedded into an ionic water-insoluble polymer matrix to provide a dosage form having rapid, reproducible, and complete dissolution profiles. These novel solid pharmaceutical dosage forms are useful in the treatment or control of a number of diseases. The present invention also provides a method for treating a disease comprising administering to a subject, in need thereof, a therapeutically effective amount of the novel solid pharmaceutical dosage form. The present invention further provides a method for preparing the pharmaceutical dosage forms.