DR. LIJUN YANG, MD
Medical Practice at Archer Rd, Gainesville, FL
License number
Florida ME82469
Category
Medical Practice
Type
Anatomic Pathology & Clinical Pathology
Address
Address
2
1600 SW Archer Rd, Gainesville, FL 32610
PO Box 918025, Orlando, FL 32891
PO Box 918025, Orlando, FL 32891
Phone
(352) 392-6840
(352) 392-4693 (Fax)
(352) 392-4693 (Fax)
Personal information
See more information about LIJUN YANG at radaris.comName
Address
Phone
10000 52Nd St, Gainesville, FL 32608
1000 52Nd St, Gainesville, FL 32608
4452 101St St, Gainesville, FL 32608
Professional information
Dr. Lijun Yang - MD (Doctor of Medicine)
Hospitals:
1600 SW Archer Rd SUITE 100371, Gainesville 32610
UNIVERSITY OF FLORIDA MEDICAL FLORIDA
1600 SW Archer Rd SUITE 100371, Gainesville 32610
1600 SW Archer Rd SUITE 100371, Gainesville 32610
UNIVERSITY OF FLORIDA MEDICAL FLORIDA
1600 SW Archer Rd SUITE 100371, Gainesville 32610
UNIVERSITY OF FLORIDA MEDICAL FLORIDA
1600 SW Archer Rd SUITE 100371, Gainesville 32610
1600 SW Archer Rd SUITE 100371, Gainesville 32610
UNIVERSITY OF FLORIDA MEDICAL FLORIDA
1600 SW Archer Rd SUITE 100371, Gainesville 32610
Education:
Medical Schools
Beijing Medical University
Graduated: 1982
Beijing Medical University
Graduated: 1982
Cellular Trans-Differentiation
US Patent:
2003022, Dec 4, 2003
Filed:
Feb 24, 2003
Appl. No.:
10/373124
Inventors:
Lijun Yang - Gainesville FL, US
International Classification:
A61K048/00, C12N005/08
US Classification:
424/093210, 435/370000
Abstract:
Highly purified hepatic stem cells are trans-differentiated into pancreatic endocrine hormone-producing cells by culturing them in vitro in a medium containing high levels of glucose. These trans-differentiated cells express insulin, glucagon, and pancreatic polypeptide, but not hepatocyte protein Hep-par. When stimulated with glucose, these cells synthesize and secrete insulin, a response enhanced by nicotinamide. Transplantation of these trans-differentiated cells into a hyperglycemic animal normalizes blood sugar levels in the animal.
Targeting Leukemia Cells
US Patent:
2003012, Jul 3, 2003
Filed:
Dec 6, 2002
Appl. No.:
10/313250
Inventors:
Lijun Yang - Gainesville FL, US
International Classification:
A61K039/395, A61K031/203, A61K031/07
US Classification:
424/146100, 424/178100, 514/569000, 514/725000
Abstract:
A molecule is targeted to a leukemia cell by first contacting the cell with a retinoid in an amount effective to increase the expression of a marker in the cell, and the contacting the cell with an agent that specifically binds the marker. For directing a molecule to an acute promyelocytic leukemia cell, the cell is contacted with all-trans retinoic acid to induce or increase expression of CD52 on the cell. The cell is then contacted with a molecule, such as an anti-CD52 antibody, that specifically binds the CD52 expressed on the cell.
Diabetes Diagnostic, Prophylactic, And Therapeutic Compositions And Methods
US Patent:
2012003, Feb 16, 2012
Filed:
Aug 5, 2011
Appl. No.:
13/204357
Inventors:
Lijun Yang - Gainesville FL, US
Vijay Koya - Hershey PA, US
Vijay Koya - Hershey PA, US
Assignee:
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. - Gainesville FL
International Classification:
A61K 39/00, C07H 21/00, C12N 15/63, C12N 5/10, A61K 31/7088, A61P 37/02, C12N 1/00, C12N 1/21, C12N 1/19, A61P 3/10, A61P 37/04, A61P 37/06, C07K 14/00, G01N 33/53
US Classification:
4241841, 530350, 530324, 536 231, 4353201, 435325, 435 792, 514 44 R, 436501, 435243, 43525233, 43525421, 435348, 435357, 435367, 435365
Abstract:
As described below, the present invention features compositions and methods featuring Pdx-1 polypeptides and fragments thereof for the diagnosis, prevention and treatment of diabetes.
Compositions And Methods For Making Insulin-Producing Cells
US Patent:
2008026, Oct 30, 2008
Filed:
Feb 23, 2005
Appl. No.:
10/598289
Inventors:
Lijun Yang - Gainesville FL, US
International Classification:
A61K 35/407, C12N 15/09, C12N 5/10
US Classification:
424 9321, 435455, 435325
Abstract:
An insulin-producing cell made by delivering a combination of at least two transcription factors, such as Pdx-1 and Pax4, to a liver cell. Cells according to the invention can be used to reduce an insulin insufficiency in a diabetic subject.
Bone Marrow Cell Differentiation
US Patent:
2004006, Apr 1, 2004
Filed:
Aug 14, 2003
Appl. No.:
10/640989
Inventors:
Lijun Yang - Gainesville FL, US
International Classification:
C12N005/08, C12N005/02, C12N005/00
US Classification:
435/372000, 435/373000
Abstract:
Human bone marrow-derived stem cells are differentiated into pancreatic endocrine marker-expressing cells in vitro by first culturing human bone marrow mononuclear cells in a tissue culture container to obtain cells that adhere to the container, and continuing to culture the adherent cells until they become morphologically homogenous; second, culturing the morphologically homogeneous cells in a medium containing high glucose levels at least until the cells express detectable levels of glucagon, insulin, and mRNAs encoding insulin, Pdx-1, and NeuroD; and third, culturing the cells in a medium containing low glucose levels, nicotinamide, and exendin 4. Transplantation of pancreatic endocrine marker-expressing cells made in this manner can reduce hyperglycemia in a diabetic animal.