LI-LI HSIAO, MD PHD
Osteopathic Medicine in Boston, MA

2009010, Apr 23, 2009

Dec 5, 2008

12/329505

Gavin J. Gordon - West Newbury MA, US
Roderick V. Jensen - Pelham MA, US
Steven R. Gullans - Natick MA, US
Li-Li Hsiao - Jamaica Plain MA, US
Raphael Bueno - Brookline MA, US

The Brigham And Women's Hospital, Inc. - Boston MA
Wesleyan University - Middletown CT

C12Q 1/68

435 6

The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from tissue samples, such as cancer tissue samples. The invention also provides sets of genes that are expressed differentially in malignant pleural mesothelioma. These sets of genes can be used to discriminate between normal and malignant tissues, and between classes of malignant tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.

8551700, Oct 8, 2013

Jul 12, 2010

12/834316

Gavin J. Gordon - West Newbury MA, US
Roderick V. Jensen - Pelham MA, US
Steven R. Gullans - Natick MA, US
Li-Li Hsiao - Jamaica Plain MA, US
Raphael Bueno - Brookline MA, US

The Brigham and Women's Hospital, Inc. - Boston MA
Wesleyan University - Middletown CT

C12Q 1/68

435 61

The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from tissue samples, such as cancer tissue samples. The invention also provides sets of genes that are expressed differentially in malignant pleural mesothelioma. These sets of genes can be used to discriminate between normal and malignant tissues, and between classes of malignant tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.

7622260, Nov 24, 2009

Sep 5, 2002

10/236031

Gavin J. Gordon - West Newbury MA, US
Roderick V. Jensen - Pelham CT, US
Steven R. Gullans - Natick MA, US
Raphael Bueno - Brookline MA, US
Li-Li Hsiao - Jamaica Plain MA, US

The Brigham and Women's Hospital, Inc. - Boston MA
Wesleyan University - Middletown CT

C12Q 1/68, G01N 33/53

435 71, 435 6

The invention provides methods for diagnosing biological states or conditions based on ratios of gene expression data from tissue samples, such as cancer tissue samples. The invention also provides sets of genes that are expressed differentially in malignant pleural mesothelioma. These sets of genes can be used to discriminate between normal and malignant tissues, and between classes of malignant tissues. Accordingly, diagnostic assays for classification of tumors, prediction of tumor outcome, selecting and monitoring treatment regimens and monitoring tumor progression/regression also are provided.