LES SEKUT
Veterinary in Ijamsville, MD
License number
Pennsylvania BV009274L
Category
Veterinary Medicine
Type
Temporary Veterinarian
Address
Address
2
Ijamsville, MD 21754
Pennsylvania
Pennsylvania
Personal information
See more information about LES SEKUT at radaris.comName
Address
Phone
11131 Innsbrook Way, Ijamsville, MD 21754
Professional information
Methods And Compositions For Modulating Ace-2 Activity
US Patent:
6592865, Jul 15, 2003
Filed:
Jun 3, 2002
Appl. No.:
10/158847
Inventors:
Tom J. Parry - Walkersville MD
Les Sekut - Ijamsville MD
Les Sekut - Ijamsville MD
Assignee:
Human Genome Sciences, Inc. - Rockville MD
International Classification:
A61K 3800
US Classification:
424 94, 514 2, 514 15
Abstract:
The invention relates to the use of angiotensin II in combination with angiotesin 1-9 to potentiate angiotensin II activity. The invention also relates to the use of combinations of angiotensin II and angiotensin 1-9 to increase vasoconstriction and to treat disorders associated with low blood pressure.
Methods And Compositions For Modulating Ace-2 Activity
US Patent:
6900033, May 31, 2005
Filed:
Jun 3, 2002
Appl. No.:
10/158825
Inventors:
Tom J. Parry - Walkersville MD, US
Les Sekut - Ijamsville MD, US
Craig A. Rosen - Laytonsville MD, US
Vivian R. Albert - Rockville MD, US
Indrajit Sanyal - Bethesda MD, US
Lili Huang - Burlington MA, US
Charles R. Wescott - Belmont MA, US
Les Sekut - Ijamsville MD, US
Craig A. Rosen - Laytonsville MD, US
Vivian R. Albert - Rockville MD, US
Indrajit Sanyal - Bethesda MD, US
Lili Huang - Burlington MA, US
Charles R. Wescott - Belmont MA, US
Assignee:
Human Genome Sciences, Inc. - Rockville MD
International Classification:
A61K038/16, C12P021/02, C12N005/06, C12N009/64
US Classification:
435 691, 530324, 514 12, 435226, 4353201, 435325
Abstract:
Binding polypeptides comprising specific amino acid sequences are disclosed that specifically bind ACE-2 protein or ACE-2-like polypeptides. The binding polypeptides can be used in methods of the invention for detecting, isolating, or purifying ACE-2 protein or ACE-2-like polypeptides in solutions or mixtures, or biological samples. The invention also relates to nucleic acid molecules encoding these ACE-2 binding polypeptides, vectors and host cells containing these nucleic acids, and methods for producing the same. The present invention also relates to methods and compositions for detecting, diagnosing, prognosing, preventing, treating or ameliorating a disease or disorder associated with aberrant ACE-2 or ACE-2 receptor expression or inappropriate function of ACE-2 or ACE-2 receptor, comprising use of ACE-2 binding polypeptides or fragments or variants thereof, that specifically bind to ACE-2.