LEONARD GAINSWORTH DENNICK
Medical Practice in Princeton, NJ
License number
Pennsylvania MD046752L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
2
Princeton, NJ 08540
Pennsylvania
Pennsylvania
Professional information
Combination Of Pravastatin And Nicotinic Acid Or Related Acid And Method For Lowering Serum Cholesterol Using Such Combination
US Patent:
5260305, Nov 9, 1993
Filed:
Jun 18, 1992
Appl. No.:
7/900378
Inventors:
Leonard G. Dennick - Princeton NJ
Assignee:
E. R. Squibb & Sons, Inc. - Princeton NJ
International Classification:
A61K 31495, A61K 3144, A61K 3134, A61K 31225
US Classification:
514255
Abstract:
A pharmaceutical combination is provided which includes an inhibitor of the enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, which is pravastatin and a pharmaceutical which reduces serum cholesterol and/or inhibits cholesterol biosynthesis by a mechanism other than inhibiting production of the enzyme HMG CoA reductase, namely, nicotinic acid (niacin) or related acid. A method for reducing serum cholesterol or inhibiting formation of or treating atherosclerosis using the above combination without causing drug-induced myopathy or rhabdomyolysis, is also provided.