LEO KOMINEK
Psychologist at Currier Dr, Kalamazoo, MI
License number
Michigan 6301009605
Category
Psychologist
Type
Psychologist
Address
Address
7895 Currier Dr, Kalamazoo, MI 49002
Phone
(269) 321-7090
Personal information
See more information about LEO KOMINEK at radaris.comName
Address
Phone
2209 Hickory Point Dr S, Portage, MI 49024
2209 Hickory Point Dr S, Portage, MI 49024
5263 Texas Dr #D, Kalamazoo, MI 49009
Kalamazoo, MI
2209 Hickory Rdg, Galesburg, MI 49053
Professional information
Leo Kominek, Portage MI
Specialties:
Psychology
Address:
7895 Currier Dr, Portage 49002
(269) 321-7090 (Phone)
(269) 321-7090 (Phone)
Languages:
English
Leo Kominek, Portage MI
Specialties:
Psychotherapist
Address:
7895 Currier Dr, Portage, MI 49002
Microbial .Delta.1-Dehydrogenation Process Using A Scavenger Of Toxic Oxygen
US Patent:
4749649, Jun 7, 1988
Filed:
May 16, 1983
Appl. No.:
6/494747
Inventors:
Timothy W. Evans - Park MI
Leo A. Kominek - Portage MI
Holly J. Wolf - Comstock Township, Kalamazoo County MI
Sheryl L. Henderson - Portage MI
Leo A. Kominek - Portage MI
Holly J. Wolf - Comstock Township, Kalamazoo County MI
Sheryl L. Henderson - Portage MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3302
US Classification:
435 61
Abstract:
A process for converting 1,2-saturated 3-keto steroids to 1,2-dehydro steroids which are useful steroid intermediates. The process involves exposing the substrate to steroid-1-dehydrogenase activity in the presence of an added electron carrier and one or more added scavengers of a toxic oxygen species.
Composition Of Matter And Process
US Patent:
4175006, Nov 20, 1979
Filed:
Oct 21, 1977
Appl. No.:
5/844366
Inventors:
Merle G. Wovcha - Kalamazoo MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C07B 2902
US Classification:
435 55
Abstract:
Valuable steroid intermediates, 9. alpha. -hydroxyandrost-4-ene-17. beta. -ol-3-one (9. alpha. --OH testosterone), 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-ol (9. alpha. --OH BN alcohol) and 9. alpha. ---hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9. alpha. --OH BN acid methyl ester), prepared by microbiological conversion of steroids having 17-alkyl side chains of 8 to 10 carbons.
Process For Preparing 9.Alpha.-Oh Bn Acid Methyl Ester
US Patent:
4214051, Jul 22, 1980
Filed:
Apr 23, 1979
Appl. No.:
6/032184
Inventors:
Merle G. Wovcha - Kalamazoo MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3316
US Classification:
435 55
Abstract:
Valuable steroid intermediates, 9. alpha. -hydroxyandrost-4-ene-17. beta. -ol-3-one (9. alpha. -OH testosterone), 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-ol (9. alpha. -OH BN alcohol) and 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9. alpha. -OH BN acid methyl ester), prepared by microbiological conversion of steroids having 17-alkyl side chains of 8 to 10 carbons.
Process For Preparing 9.Alpha.-Oh Bn Alcohol
US Patent:
4214052, Jul 22, 1980
Filed:
Apr 23, 1979
Appl. No.:
6/032185
Inventors:
Merle G. Wovcha - Kalamazoo MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3316
US Classification:
435 55
Abstract:
Valuable steroid intermediates, 9. alpha. -hydroxyandrost-4-ene-17. beta. -ol-3-one (9. alpha. -OH testosterone), 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-ol (9. alpha. -OH BN alcohol) and 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9. alpha. -OH BN acid methyl ester), prepared by microbiological conversion of steroids having 17-alkyl side chains of 8 to 10 carbons.
Process For Preparing 9.Alpha.-Oh Bn Alcohol
US Patent:
4226936, Oct 7, 1980
Filed:
Apr 23, 1979
Appl. No.:
6/032189
Inventors:
Merle G. Wovcha - Kalamazoo MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3316
US Classification:
435 55
Abstract:
Valuable steroid intermediates, 9. alpha. -hydroxyandrost-4-ene-17. beta. -ol-3-one (9. alpha. -OH testosterone), 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-ol (9. alpha. -OH BN alcohol) and 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9. alpha. -OH BN acid methyl ester), prepared by microbiological conversion of steroids having 17-alkyl side chains of 8 to 10 carbons.
Process For Preparing 9.Alpha.-Oh Bn Acid Methyl Ester
US Patent:
4223092, Sep 16, 1980
Filed:
Apr 23, 1979
Appl. No.:
6/032188
Inventors:
Merle G. Wovcha - Kalamazoo MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Frederick J. Antosz - Kalamazoo MI
John M. Beaton - Portage MI
Alfred B. Garcia - Kalamazoo MI
Leo A. Kominek - Portage MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3316
US Classification:
435 55
Abstract:
Valuable steroid intermediates, 9. alpha. -hydroxyandrost-4-ene-17. beta. -ol-3-one (9. alpha. -OH testosterone), 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-ol (9. alpha. -OH BN alcohol) and 9. alpha. -hydroxy-3-ketobisnorchol-4-en-22-oic methyl ester (9. alpha. -OH BN acid methyl ester), prepared by microbiological conversion of steroids having 17-alkyl side chains of 8 to 10 carbons.
1,2-Dehydrogenation Of Steroidal 21-Esters With Arthrobacter Simplex Or Bacterium Cyclooxydans
US Patent:
5225335, Jul 6, 1993
Filed:
Sep 12, 1989
Appl. No.:
7/582954
Inventors:
Leo A. Kominek - Portage MI
Holly J. Wolf - Plainwell MI
Paula S. Steiert - Lawton MI
Holly J. Wolf - Plainwell MI
Paula S. Steiert - Lawton MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3302
US Classification:
435 61
Abstract:
The present invention involves processes for 1,2-dehydrogenation of. DELTA. sup. 4 -3-keto C. sub. 21 -hemiester steroids of formula (I) ##STR1## with Arthrobacter simplex or Bacterium cyclooxydans to produce the corresponding. DELTA. sup. 1,4 -3-keto C. sub. 21 hemiester of formula (II) ##STR2## or free alcohol thereof with improved yields. The advantage is that the processes utilize higher substrate concentrations and give shorter reaction times than previously were known.
.Delta..sup.1 -Dehydrogenation With Heat Or Air-Dried B. Cyclooxidans
US Patent:
4704358, Nov 3, 1987
Filed:
Apr 8, 1985
Appl. No.:
6/721011
Inventors:
Leo A. Kominek - Portage MI
Holly J. Wolf - Comstock Township, Kalamazoo County MI
Holly J. Wolf - Comstock Township, Kalamazoo County MI
Assignee:
The Upjohn Company - Kalamazoo MI
International Classification:
C12P 3302, C12N 104
US Classification:
435 61
Abstract:
Disclosed and claimed is an improved microbial bioconversion to produce 1,2-dehydro steroids from their corresponding 1,2-saturated derivatives.