LAWRENCE HORSTMAN
Medical Practice at 5 Ave, Miami, FL
License number
Florida 29402
Issued Date
Jun 13, 1990
Effective Date
Sep 26, 2014
Expiration Date
Aug 31, 2012
Category
Health Care
Type
Clinical Laboratory Personnel
Address
Address
3301 NE 5Th Ave #704, Miami, FL 33137
Phone
(305) 243-6617
Professional information
Expanded Utility Of Red Cell-Derived Microparticles (Rmp) For Treatment Of Bleeding
US Patent:
2013031, Nov 28, 2013
Filed:
Jan 27, 2012
Appl. No.:
13/982224
Inventors:
Yeon S. Ahn - Miami FL, US
Lawrence L. Horstman - Miami FL, US
Wenche Jy - Miami FL, US
Lawrence L. Horstman - Miami FL, US
Wenche Jy - Miami FL, US
Assignee:
UNIVERSITY OF MIAMI - Miami FL
International Classification:
A61K 35/18
US Classification:
424533, 435325
Abstract:
Red blood cell membrane derived microparticles (RMP) are safe, economical, effective hemostatic agents in the treatment of a wide range of bleeding conditions and can, therefore, be considered as universal hemostatic agents. Effective RMP are produced from red blood cells using a high-pressure extrusion membrane shear process. The RMP can be lyophilized after production and retain activity even when stored at room temperature. RMP can be administered to original donors (autologous treatment), thus avoiding transfusion complications, or can be administered to blood type compatible recipients. RMP produced from type O, Rh negative red cells can be given to any person regardless of blood type. RMP can be administered to reduce excessive bleeding resulting from trauma, surgeries, invasive procedures and various bleeding disorders such as platelet disorders, either congenital or acquired, and coagulation disorders, either congenital or acquired. Administration of RMP prepared according to the invention demonstrates effectiveness in safely reducing bleeding.