LARRY D. SUTTON, MD
Osteopathic Medicine at Highway 1, Fairfield, IA
License number
Iowa 30316
Category
Osteopathic Medicine
Type
Emergency Medicine
Address
Address
1829 Highway 1, Fairfield, IA 52556
Phone
(641) 472-4079
Professional information
Broad Spectrum Beta-Lactamase Inhibitors
US Patent:
2009013, May 21, 2009
Filed:
Oct 9, 2008
Appl. No.:
12/248760
Inventors:
Larry Sutton - Fairfield IA, US
Sophia Yu - Fairfield IA, US
Sophia Yu - Fairfield IA, US
International Classification:
A61K 31/545, C07D 501/16, A61K 31/546
US Classification:
514203, 540215, 540224, 540222, 514202, 514200
Abstract:
Broad spectrum beta-lactamase inhibitors. Certain inhibitors also exhibit potent antibiotic activity in addition to beta-lactamase inhibition. Compounds of the invention are designed such that on cleavage of the beta-lactam ring reactive moieties are generated which can inactivate beta-lactamase. Also provided are methods of making beta-lactamase inhibitors and beta-lactam antibiotics exhibiting such inhibition. Additionally provided are pharmaceutical compositions for treatment or prevention of bacterial infections and methods of treatment of such infections.