Inventors:
Joseph Dellaria - Woodbury MN, US
Tushar Kshirsagar - Woodbury MN, US
Shri Niwas - Maple Grove MN, US
William Moser - St. Paul MN, US
Joan Moseman - Lake Elmo MN, US
Kyle Lindstrom - Houlton WI, US
Azim Celebi - Clark NJ, US
John Gerster - Woodbury MN, US
Philip Heppner - Forest Lake MN, US
Joshua Wurst - North St. Paul MN, US
International Classification:
A61K 31/44, A61K 31/437, A61K 31/496, A61P 31/12, A61P 35/00, C07D 401/02, C07D 401/14, C07D 471/02
US Classification:
514253030, 514293000, 514303000, 544362000, 546118000, 546082000
Abstract:
Imidazo ring systems, which include, for example, imidazopyridine, imidazoquinoline, 6,7,8,9-tetrahydroimidazoquinoline, imidazonaphthyridine, and 6,7,8,9-tetrahydroimidazonaphthyridine compounds substituted at the 1-position and/or the 2-position, pharmaceutical compositions containing these compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.