Inventors:
Lilla Boroczky - Mount Kisco NY, US
Luyin Zhao - White Plains NY, US
Kwok Pun Lee - Flushing NY, US
Assignee:
KONINKLIJKE PHILIPS ELECTRONICS, N.V. - Eindhoven
International Classification:
G06K 9/62
Abstract:
A method for computer aided detection (CAD) and classification of regions of interest detected within HRCT medical image data includes post-processing machine learning to maximize specificity and sensitivity of the classification to realize a reduction in number of false positive detections reported. The method includes training a classifier on a set of medical image training data selected to include a number of true and false regions, wherein the true and false regions are identified by a CAD process, and automatically segmented, wherein the segmented training regions are reviewed by at least one specialist to classify each training region for its ground truth, i.e., true or false, essentially qualifying the automatic segmentation, wherein a feature pool is identified and extracted from each segmented region, and wherein the pool of features is processed by genetic algorithm to identify an optimal feature subset, which subset is used to train a support vector machine, detecting, within non-training medical image data, regions that are candidates for classification, segmenting the candidate regions, extracting a set of features from each segmented candidate regions and classifying the candidate region using the support vector machine after training in accordance with the optimal feature subset, and processing the set of candidate features.