Inventors:
Garry Cole - Toledo OH, US
Kun Li - Ann Arbor MI, US
Kalpathi Seshan - Toledo OH, US
International Classification:
A61K039/005, A61K039/008, C07H021/04, C12N001/10, C12N015/74, C07K014/44
US Classification:
424/191100, 424/269100, 435/069300, 435/258100, 435/320100, 530/350000, 536/023600
Abstract:
The present invention provides compositions and methods of use of urea amidohydrolase (Ure) antigens and polynucleotides encoding the Ure antigens for generating an immunological response in an individual and in therapeutic and diagnostic applications of infections due to pathogenic Coccidioides spp. fungi, such as or