Inventors:
Vincent Manetta - Bordentown NJ, US
Linda Mahoney - Phoenixville PA, US
Michael Nordsiek - Berwyn PA, US
Kodumudi Balaji - Lansdale PA, US
Jay Dorrell - Vicksburg MI, US
International Classification:
A61K031/192, A61K009/00
Abstract:
A package comprising components which, upon being mixed, are capable of forming a pharmaceutical composition that is effective in treating acne, the composition tending to degrade prematurely, one of the components comprising an oxidizing agent and another of the components comprising an antibiotic which is effective against acne-associated bacterial species, the components separated one from the other in the package, one component having a viscosity within about 50% of the viscosity of the other component. In addition, a package comprising: (A) components which, upon being mixed, are capable of forming a pharmaceutical composition that is effective in treating acne, one of the components comprising a benzoyl peroxide gel and another of the components comprising a gel of erythromycin and hydroxypropylcellulose; and (B) containers for holding the components in the package separated one from the other; the components having viscosities such that, upon the application of a uniform forces to the components, substantially equal volumes of the components are capable of being dispensed simultaneously from the containers.