Inventors:
Rhoda Alani - Baltimore MD, US
Alison Young - Baltimore MD, US
Klaus Busam - Chatham NJ, US
International Classification:
C12Q001/68, G01N033/574
Abstract:
A tissue or biopsy sample is evaluated to determine if the sample is early-stage melanoma by determining the level of inhibitor of DNA-binding protein 1 (Id1) expression in cells of the sample; and comparing the determined amount of Id1 to a reference level. The presence of levels of Id1 in cells of the sample in excess of the reference level indicates that the sample is early-stage melanoma.