Inventors:
K. Ranga R. Krishnan - Chapel Hill NC, US
Kishore M. Gadde - Durham NC, US
Assignee:
Duke University - Durham NC
International Classification:
A61K 9/14, A61K 31/55, A61K 31/44, A61K 31/42, A61K 31/40, A61K 31/335, A61K 31/19, C07D 223/14, A01N 43/00, A01N 43/46, A01N 43/42, A01N 43/80, A01N 43/36, A01N 43/32, A01N 47/10, A01N 37/00
US Classification:
51421402, 424489, 514217, 514288, 514379, 514424, 514452, 514483, 514557, 540576
Abstract:
Disclosed are pharmaceutical compositions comprising mirtazapine and an anticonvulsant drug. Also disclosed are methods of preventing weight gain associated with the administration of mirtazapine comprising identifying a patient to whom mirtazapine is to be administered and administering to said patient a pharmaceutical composition comprising mirtazapine and an anticonvulsant drug. Further disclosed are methods of increasing the efficacy of mirtazapine comprising identifying a patient to whom mirtazapine is to be administered and administering to said patient a pharmaceutical composition comprising mirtazapine and an anticonvulsant drug.