Kirk Ute Knowlton
Physician in Escondido, CA
License number
Utah 9626726-1205
Issued Date
Dec 10, 2015
Expiration Date
Jan 31, 2018
Category
Physician
Type
Physician & Surgeon
Address
Address
Escondido, CA
Education
UNIVERSITY OF UTAH SCHOOL OF MEDICINE
Professional information
Method And Materials For Use In Diagnosing Viral Myocarditis
US Patent:
7867476, Jan 11, 2011
Filed:
Mar 24, 2005
Appl. No.:
10/591092
Inventors:
Kirk Knowlton - Escondido CA, US
Sotirios Tsimikas - San Diego CA, US
Sotirios Tsimikas - San Diego CA, US
Assignee:
The Regents of the University of California - Oakland CA
International Classification:
A61K 49/00
US Classification:
424 91, 424 111, 424 149, 424 92, 435 5
Abstract:
The invention consists of assay methods, assay kits and antibodies for detecting the polypeptide fragments of dystrophin protein cleavage by enteroviral protease 2A as a result of an enteroviral infection in the heart. The presence of dystrophin cleavage products in the myocytes or blood of a subject is diagnostic for enteroviral infection and myocarditis resulting therefrom.
Method And Materials For Use In Diagnosing Viral Myocarditis
US Patent:
2011009, Apr 28, 2011
Filed:
Jan 5, 2011
Appl. No.:
12/985296
Inventors:
Kirk Knowlton - Escondido CA, US
Sotirios Tsimikas - San Diego CA, US
Sotirios Tsimikas - San Diego CA, US
International Classification:
A61K 49/00, C07K 16/18
US Classification:
424 91, 5303913
Abstract:
The invention consists of assay methods, assay kits and antibodies for detecting the polypeptide fragments of dystrophin protein cleavage by enteroviral protease A as a result of an enteroviral infection in the heart. The presence of dystrophin cleavage products in the myocytes or blood of a subject is diagnostic for enteroviral infection and myocarditis resulting therefrom.