KIMBRA KENNEY, M.D.
Neurology at Lee Hwy, Arlington, VA
License number
Virginia 0101052755
Category
Neurology
Type
Neurology
Address
Address
6605 Lee Hwy, Arlington, VA 22205
Phone
(202) 782-3321
(703) 532-4110
(703) 532-4110
Professional information
Method Of Detecting Transmissible Spongiform Encephalopathies
US Patent:
6406860, Jun 18, 2002
Filed:
Jun 7, 1999
Appl. No.:
09/326976
Inventors:
Gary Hsich - Philadelphia PA
Kimbra Kenney - Arlington VA
Michael G. Harrington - La Canada CA
Kimbra Kenney - Arlington VA
Michael G. Harrington - La Canada CA
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
California Institute of Technology - Pasadena CA
California Institute of Technology - Pasadena CA
International Classification:
G01N 3353
US Classification:
435 71, 424 91, 4241301, 4241381, 435 5, 435 792, 435 793, 436811
Abstract:
This invention provides an improved assays for the detection of transmissable spongiform encephalopathies (TSEs) in humans and non-human mammals. The methods involve detecting the presence or absence of 14-3-3 proteins in cerebrospinal fluid from the tested organism. Elevated levels of 14-3-3 are indicative of transmissable spongiform encephalopathies, in particular Cretzfeldt-Jacob disease in humans or mad cow disease in bovines).
Method Of Detecting Transmissible Spongiform Encephalopathies
US Patent:
5998149, Dec 7, 1999
Filed:
Apr 5, 1996
Appl. No.:
8/630961
Inventors:
Gary Hsich - Philadelphia PA
Kimbra Kenney - Arlington VA
Clarence J. Gibbs - Washington DC
Michael G. Harrington - La Canada CA
Kimbra Kenney - Arlington VA
Clarence J. Gibbs - Washington DC
Michael G. Harrington - La Canada CA
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
and Human Services - Washington DC
International Classification:
G01N 3353, G01N 100, A61K 4904
US Classification:
435 71
Abstract:
This invention provides an improved assays for the detection of transmissible spongiform encephalopathies (TSEs) in humans and non-human mammals. The methods involve detecting the presence or absence of 14-3-3 proteins in cerebrospinal fluid from the tested organism. Elevated levels of 14-3-3 are indicative of transmissible spongiform encephalopathies, in particular Creutzfeldt-Jacob disease in humans or mad cow disease in bovines).